Excipients and delivery systems for pharmaceutical formulations

書誌事項

Excipients and delivery systems for pharmaceutical formulations

edited by D. R. Karsa, R. A. Stephenson

(Special publication / Royal Society of Chemistry, no. 161)

The Royal Society of Chemistry, 1995

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注記

Proceedings of the Formulate '94 Symposium

内容説明・目次

内容説明

Excipients and Delivery Systems for Pharmaceutical Formulations focuses on the many problems associated with the formulation of drugs whether in tablet, liquid or capsule form. Areas covered include drug delivery systems, binding and coating, tableting, drug targeting and excipient selection, as well as aspects of good manufacturing practice. The book covers many areas of pharmaceutical excipients and delivery systems that will interest both formulators and producers of these materials. It describes a representative range of binders, coatings and controlled release systems, including cellulose derivatives, starches, alginates, chitosan, xanthan gum and glycerides. Other topics discussed include attempts to globalise the use of some excipients, trends in medical and pharmaceutical fields to the year 2000, and the US Food and Drug Administration's approach to bulk pharmaceutical chemical production. Excipients and Delivery Systems for Pharmaceutical Formulations will provide a useful introduction for those relatively unfamiliar with this highly technical subject, as it gives broad coverage of a very diverse area. The book will also be essential reading for those more experienced in the production and formulation of pharmaceutical excipients, as it documents some of the most innovative recent developments.

目次

  • Excipients Selection for World-wide Marketed Dosage Forms
  • Excipients to the Year 2000
  • An FDA Perspective on Bulk Pharmaceutical Chemical GMPS, Control and Validation
  • Pharmaceutical Products - from Tablets to Topicals. Applications for Cross-linked Acrylic Acid Polymers
  • Selection and Optimisation of Excipients in Transdermal Delivery Systems
  • Characterisation of Powder Surfaces: Understanding Sources of Variability in Products
  • Binders for Granules and Tablets
  • Extension of Delivery of Microcapsules Manufactured by the E-Cap Pressure Shock Wave Process
  • A Programmable Excipient - Delta Starch
  • Drug Delivery Systems with Alginate and Chitosan
  • Hydration Induced Swelling of Alginate Based Matrix Tablets at GI-Tract pH Conditions
  • Xanthan Gum in Hydrophilic Matrix Drug Delivery Systems
  • Formulations of Softgels for Improved Oral Delivery of Hydrophobic Drugs
  • The Use of Glycerides as Controlled Release Matrices
  • Enteric Coatings with Aqueous Polymethacrylate Dispersions
  • Water Soluble Cellulose Ethers in Aqueous Film Coating
  • Some Formulation Factors Involved in Hydroxypropyl Methycellulose Controlled Release Matrices
  • Subject Index.

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