Bibliographic Information

GABA[A] receptors and anxiety : from neurobiology to treatment

volume editors, Giovanni Biggio ... [et al.]

(Advances in biochemical psychopharmacology / series editors, Erminio Costa [and] Paul Greengard, v. 48)

Raven Press, c1995

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Note

Proceedings of the Symposium on Anxiety of the 8th Sardinian Conference on Neuroscience held at Villasimius (Cagliari), Italy, in May 1995

Includes bibliographical references and index

Description and Table of Contents

Description

This volume examines recent research on the molecular biology, biochemistry and physiopathology of anxiety disorders and the molecular and clinical pharmacology of anxiolytic drugs. The text focuses primarily on the molecular biology, pharmacology and physiopathology of GABA a receptors in the mammalian nervous system. Topics covered include: pharmacology of recombinant GABA a receptors; cellular localization; pharmacology and regulation of GABA a receptor subtypes in vivo; neuroactive steroid modulation of GABA a receptors; animal models of different anxiety disorders; clinical pharmacology of anxiolytic drugs; and a search for a new anticonvulsant and anxiolytic benzodiazepine devoid of side effects and tolerance liability.

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