Interleukin-5 and its receptor system : from genes to disease
著者
書誌事項
Interleukin-5 and its receptor system : from genes to disease
（Molecular biology intelligence unit）
R.G. Landes, c1995
- タイトル別名
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Interleukin five and its receptor system
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
A key question regarding the action of IL-5 in responsive cells has been the molecular mechanism of signal transduction cascade after IL-5 binding to the functional IL-5 receptor (IL-5R). In this volume the history of the initial discovery of the IL-5 activity that appeared to be involved in growth and differentiation of B cells and eosinophils is first briefly summarized, and the developments that lead to the molecular characterization of IL-5 are outlined. The author also describes recent advances of IL-5 and IL-5R research in the study of structure, physiologic functions and unique mode of receptor-mediated signaling. Finally, the roles of IL-5 in the pathophysiology of allergic diseases and immunodeficiency are summarized.
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