Alzheimer's disease : a medical companion

著者

書誌事項

Alzheimer's disease : a medical companion

Alistair Burns, Robert Howard, William Pettit ; foreword by Raymond Levy

Blackwell Science, 1995

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注記

Includes bibliographical references (p. 148-154) and index

内容説明・目次

内容説明

There is currently no published text for GPs on the management of Alxheimer's Disease, one of the major neurodegenerative diseases. This book will provide both up-to-date information on the epidemiology and aetiology of the disease, and a full clinical picture with details on diagnosis and management options, including pharmacological and non-drug (psychological) therapies. Management of the disease from the primary care angle will be discussed, reflecting the current changes within the NHS structure. The effect on the family supporting the patient, who is frequently disorientated and out of control of life, is stressful and there will be a chapter suggesting some strategies for the GP to use in alleviating this. This book takes a broad look at the management of this disease in the primary care setting, in which the majority of patients are treated, in order to encourage a thorough understanding and effective clinical approach.

目次

  • Foreword
  • Preface
  • Introduction
  • Epidemiology:
  • The normal population
  • Definition of terms
  • Methods
  • Epidemiology of dementia
  • Epidemiology of alzheimer's disease
  • Survival
  • Aetiology:
  • Risk factors
  • The Biological Basis of Alzheimer's Disease: Neuropathology
  • Neurochemistry
  • Molecular biology
  • The Clinical Picture:
  • Early signs
  • The five As of Alzeimer's disease
  • Other features
  • The differential diagnosis of alzheimer's disease
  • Cortical or subcortical dementia? Rating of dementia severity
  • Benign senscent forgetfulness and age-associated memory impairment
  • The Diagnostic Process:
  • History
  • Physical examination
  • Examination of the mental state
  • Assessment of the cognitive state
  • Further investigations
  • Clinical criteria
  • Peripheral markers
  • Management:
  • Pharmacological treatment of cognitive deficits
  • Pharmacological treatment of non-cognitive features
  • Non-pharmacological therapies
  • General practice management
  • Carers and Services:
  • Carers
  • Services
  • Cost of care
  • The Alzheimer's Disease Society
  • A View from Primary Care:
  • The size of the problem
  • Case finding and screening in primary care
  • Management
  • Drug treatment
  • Family and carers
  • Audit
  • The future
  • Legal and Ethical Issues:
  • Legal aspects
  • Medical ethics
  • Appendix 10.1 - Useful addresses
  • Future Prospects:
  • Molecular biology
  • Genetics
  • Diagnosis
  • Neuroimaging
  • Risk factors
  • Treatments
  • References
  • Further Reading
  • Index

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