DNA-protein : structural interactions

著者

    • Lilley, David M. J. (David Malcolm James)

書誌事項

DNA-protein : structural interactions

edited by David M. J. Lilley

(Frontiers in molecular biology, 7)

Oxford University Press, 1995

  • pbk.
  • hbk.

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注記

Includes bibliographical references and index

内容説明・目次

巻冊次

pbk. ISBN 9780199634538

内容説明

Many processes in the genetic life of the cell requires the specific interaction between proteins and DNA. While DNA is normally thought of as a straight double helix, it can be distorted by bending and twisting, and these alterations are critical to a number of cellular processes. These include transcription (by which the genetic message is read), recombination (rearrangements by which new combinations of genes come about), and the repair of DNA damage. An interesting group of the proteins have the important role of recognising and manipulating DNA structure. This book draws together themes from different parts of molecular biology to bring out the importance of DNA structure in the interactions between proteins and DNA, and generates a new perspective on DNA-protein interactions.

目次

  • 1. DNA-protein interaction at high resolution
  • 2. DNA bending by sequence and proteins
  • 3. Enzymes that supercoil DNA
  • 4. Recognition of DNA damage and repair
  • 5. Structure-recognition by DNA junction resolving enzymes
  • 6. Site-specific recombinases and their interactions with DNA
  • 7. The HMG-box domain
巻冊次

hbk. ISBN 9780199634545

内容説明

Many processes in the genetic life of the cell require a specific interaction between proteins and DNA. While DNA is normally thought of as a straight double helix, it can be distorted by bending and twisting, and these alterations are critical to a number of cellular processes. These include transcription (by which the genetic message is read), recombination (rearrangements by which new combinations of genes come about), and the repair of DNA damage. An interesting group of proteins have the important role of recognizing and manipulating DNA structure. This text explores the importance of DNA structure in the interactions between proteins and DNA in order to generate a new perspective on DNA-protein.

目次

1.: DNA-protein interaction at high resolution. 2.: DNA bending by sequence and proteins. 3.: Enzymes that supercoil DNA. 4.: Recognition of DNA damage and repair. 5.: Structure-recognition by DNA junction resolving enzymes. 6.: Site-specific recombinases and their interactions with DNA. 7.: The HMG-box domain

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