Diabetic neuropathy : new concepts and insights : proceedings of the 3rd International Symposium on Diabetic Neuropathy, Kanagawa, 3-5 November 1994

書誌事項

Diabetic neuropathy : new concepts and insights : proceedings of the 3rd International Symposium on Diabetic Neuropathy, Kanagawa, 3-5 November 1994

editors, N. Hotta ... [et al.]

(International congress series, no. 1084)

Elsevier, 1995

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注記

"A satellite symposium of the 15th International Diabetes Federation (IDF) Congress in Kobe, held on November 6-11, 1994"--Pref

内容説明・目次

内容説明

This congress was held as a Satellite Symposium of the 15th International Diabetes Federation (IDF) Congress in Kobe, held on November 6-11, 1994. Over the last decade research on diabetic neuropathy has focussed our attention on new approaches to its pathogenesis and treatment. A number of hypotheses concerned with etiology have been proposed, which may, for convenience, be grouped under the headings "metabolic", "vascular", "trophic" and "other". It is well known that much research based on these hypotheses have contributed to the resulting therapeutically valuable developments. However, despite the progress in these aspects, the precise mechanisms still remain one of the most important unsolved problems in biochemical, physiological and/or pathological research. Researchers and clinicians from all over the world gathered together to discuss these varied topics.

目次

  • Plenary lectures - recent studies in experimental diabetic neuropathy, P.A. Low, two separate mechanisms for the glucose inhibition of myo-inositol transport, T.C. Hohman and H. Moo Kwon, clinical investigation of epalrestat, an aldose reductase inhibitor on diabetic neuropathy in Japan multi-centre study, N. Hotta et al
  • educational lectures - a history of diabetic neuropathy in the 19th century, J.D. Ward
  • nerve blood flow - effects of aminoguanidine on vasculature and nerves of streptozotocin-diabetic rats, M. Dewhurst et at, effects of endothelin receptor antagonism on peripheral nerve function in experimental diabetes, E.J. Stevens and D.R. Tomlinson
  • nerve growth factors and others - a role for insulin in small sensory nerve function in man, C.A. Delaney et al, abnormal intramuscular nerve sprouting after partial denervation in streptozocin-induced diabetic rats, M. Terada et al
  • metabolism - effects of alpha-lipoic acid and glutathione on systemic and sciatic nerve antioxidant levels in experimental diabetes, P.S. van Dam et al, pharmacological evidence suggesting compromised cyclo-oxygenase activity in the streptozotocin model of diabetic neuropathy, P.O.O. Julu and G.A. Jamal, effect of a AL-01576 on brain neurotransmission in STZ-diabetic and galactose-fed rats, I. Obrosova et al, microvascular and metabolic abnormalities in the spontaneously diabetic dog, R.A. Malik et al
  • electrophysiologic measurements and correlation - changes in foot loading and pressure patterns during standing of patients with diabetic neuropathy, P. Schaff et al, impaired sensory nerve function in insulin resistant rats, C.A. Delaney et al, newly developed method to assess autonomic nerve function in diabetic patients, T. Matsuoka et al
  • clinical trials - clinical and neurophysiological effects of epalrestat on diabetic neuropathy, M. Ikezawa et al, effect of intracavernous injection with papaverine on diabetic impotence in Japan, Y. Takahashi et al, sensorimotor neuropathy and cardiac autonomic function tests in fibrocalculous pancreatic diabetes (FCPD), A.K. Das amd R. Govindan.

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