Dopamine receptor agonists
Author(s)
Bibliographic Information
Dopamine receptor agonists
(New horizons in therapeutics)
Plenum Press, c1984
Available at 4 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Proceedings of the Annual Smith, Kline, and French Research Symposium on New Horizons in Therapeutics, held in Philadelphia, Feb. 23-24, 1983
Includes bibliographies and index
Description and Table of Contents
Description
Dopamine, in addition to its importance as a precursor of norepinephrine, is now known to be an important neurotransmitter in regulating functional activities in a number of major organ systems, including the central ner- vous system. the cardiovascular system, the kidney, and the gut. Recent advances in our understanding of the functional role of dopamine, its mechanism of action and the pharmacology of dopaminergic agents have occurred on a broad front. The last few years have witnessed significant progress in the identification and classification of central and peripheral dopamine receptors and the factors that affect their responsiveness to inhibitory and stimulatory ligands. These advances have been paralleled by new insights into the contribution of alterations in dopaminergic reg- ulation in causing disease and the utility of dopamine agonists and an- tagonists as therapeutic modalities. This volume, the first in a series of publications arising from the annual Smith Kline and French Research Symposium on New Horizons in Therapeutics, provides a comprehensive survey of current research on peripheral dopamine receptors and the physiologic and therapeutic con- sequences of stimulating pre-and postsynaptic dopamine receptors. Research in dopamine pharmacology mirrors the remarkable ad- vances that are occurring in the field of pharmacology at large as a con- sequence of the involvement of an ever-larger number of scientific dis- ciplines in the study of drug action.
Table of Contents
I. Dopamine Receptors.- 1 Pharmacological and Biochemical Characterization of Two Categories of Dopamine Receptor.- 2 Radioligand Binding Studies of Agonist Interactions with Dopamine Receptors.- 3 Quantitative Assay of Dopamine Receptor Subtypes.- 4 Structure-Activity Relationships of Dopamine Receptor Agonists.- 5 Peripheral Dopamine Receptors.- 6 Pharmacological Significance of Pre- and Postsynaptic Dopamine Receptors.- II. Dopamine Agonist Function and Pharmacology.- 7 Dopamine: An Endogenous Peripheral Neurotransmitter.- 8 Vascular Dopamine and Dopamine Receptor Agonists.- 9 Dopamine Receptor Agonists and Hypertension.- III. Critical Concepts of Physiological and Molecular Mechanisms of Cardiovascular and Renal Function.- 10 Role of Inflammatory Cells in Metabolic and Cellular Alterations Underlying the Exaggerated Renal Prostaglandin and Thromboxane Synthesis in Ureter Obstruction.- 11 The Kidney and Hypertension.- 12 Molecular Mechanisms of Vasodilatation.- IV. Clinical Applications.- 13 The Relationship of Receptor Actions of Dopamine Agonists to Their Clinical Effects.- 14 Hemodynamic Factors Involved in the Regulation of Sodium Balance.- 15 Dopaminergic Mechanisms in the Control of Aldosterone Secretion: A. Critical Appraisal.- 16 Dopamine Agonists/Antagonists in the Treatment of Gastrointestinal Diseases.- 17 The Use of Dopamine Agonists and Antagonists in Neurology.- References.
by "Nielsen BookData"