Bibliographic Information

Sequence analysis primer

edited by Michael Gribskov and John Devereux

(UWBC biotechnical resource series)

Oxford University Press, c1992

Available at  / 4 libraries

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Includes references and index

Description and Table of Contents

Description

Computerized sequence analysis is an integral part of biotechnological research, yet many biologists have received no formal training in this important technology. Sequence Analysis Primer offers the necessary background to enter this exploding field and helps more seasoned researchers to fine-tune their approach. Compatible with most sequence analysis programs, the primer covers basic data manipulation, and offers valuable advice for overcoming common problems. A detailed example giving steps for characterizing a new gene sequence provides users with "hands-on" experience when combined with their current software.

Table of Contents

1: Peter M. Rice, Keith Elliston, and Michael Gribskov: DNA 1.1: Sequencing Project Management 1.2: Identification of Simple Sites and Transcriptional Signals 1.3: Coding Region Identification 1.4: RNA Structure 1.5: DNA Structure 1.6: Summary 2: Roland Luthy and David Eisenberg: Protein 2.1: Physical Properties 2.2: Structural Properties 2.3: Summary 3: David J. States and Mark S. Boguski: Similarity and Homology 3.1: Similarity versus Homology 3.2: Dot Matrix Methods 3.3: Dynamic Programming Methods 3.4: Scoring Systems 3.5: Summary 4: Lisa Caballero: Practical Aspects: Analysis of Notch 4.1: cDNA Sequence Analysis 4.2: Protein Analysis: Determining Structure and Function 4.3: Genomic DNA 4.4: Summary

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