Bacterial toxins and virulence factors in disease

書誌事項

Bacterial toxins and virulence factors in disease

edited by Joel Moss ... [et al.]

(Handbook of natural toxins, v. 8)

M. Dekker, c1995

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors, providing recent information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. A wide variety of toxic proteins, including the toxins that cause diptheria, cholera, pertussis, shigellosis, tetanus, botulism and anthrax, are discussed.;The work is aimed at microbiologists, biochemists, endocrinologists, toxicologists, infectious disease specialists, pathologists, public health officials, and upper-level undergraduate and graduate students in these disciplines.

目次

  • Biosynthesis and targeting of pertussis toxin
  • diphthamide - the toxin target in protein synthesis elogation factor 2
  • leukocidines
  • heat-stable enterotoxin of escherichia coli
  • therapeutic effects of botulinum toxins
  • endotoxin - a mediator of and potential therapeutic target
  • zot and ace toxins of vibrio cholerae
  • ADP-ribosylation factors - a family of guanine nucleotide-binding proteins that activate cholera toxin and regulate vesicular transport
  • liposomes and vehicles for vaccines
  • GTP-binding proteins as the substrate of pertussis toxin-catalyzed ADP-ribosylation
  • modification of actin and rho proteins by clostridial ADP-ribosylating toxins
  • muramyl peptides as exotoxins - bordetella tracheal cytotoxin
  • adenylyl cyclase toxin from bordetella pertussis
  • clostridium difficile and its toxins
  • structure and function of e. coli heat labile enterotoxin and cholera toxin B-pentamer
  • anthrax toxins
  • the diphtheria toxin receptor
  • bacterial ADP-ribosyltransferases
  • bordetella pertussis - determinants of virulence
  • shiga and shiga-like (vero) toxins
  • cholera toxin and related enterotoxins of gram-negative bacteria.

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