Molecular medicine
著者
書誌事項
Molecular medicine
(Lecture notes)
Blackwell Science, c1995
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注記
Includes index
内容説明・目次
内容説明
Lecture Notes on Molecular Medicine is a core text that aims to give a concise and clear introduction to how molecular biology works, and how it is used to understand and treat human disease. It will appeal to a wide ranging audience, from medical students to higher examination candidates, who want a straightforward introduction to one of the most important growth areas in modern medicine.
目次
- 1. Basic Principles:
- DNA
- RNA Structure
- DNA replication and transcription: it's all the genes
- Gene expression: making proteins
- Gene transcription: transmitting the code
- Translation: reading the code
- 2.Manipulation of DNA/RNA:
- Preparation of nucleic acid
- Cutting and pasting DNA (restriction enzymes and ligases)
- Extending and chewing DNA (polymerases and nucleases)
- Making RNA from DNA and vice versa: RNA Pol and reverse transcriptase
- 3. Molecular techniques:
- Blotting
- Hybridization
- Transfection and transformation: selection and screening
- DNA analysis
- RNA analysis
- Nucleic acid-protein interactions
- Transgenic animals (adding genes)
- Knockout animals (deleting genes)
- 4. Understanding genetics:
- Evolution of the human genome
- Inheriting genes
- Diversity in the genome: why are we different? Identifying genetic differences between individuals
- Finding genes
- 5. Molecular medicine in practice:
- Biotechnology in clinical medicine
- Index
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