書誌事項

Molecular medicine

John Bradley, David Rubenstein, David Johnson

(Lecture notes)

Blackwell Science, c1995

この図書・雑誌をさがす
注記

Includes index

内容説明・目次

内容説明

Lecture Notes on Molecular Medicine is a core text that aims to give a concise and clear introduction to how molecular biology works, and how it is used to understand and treat human disease. It will appeal to a wide ranging audience, from medical students to higher examination candidates, who want a straightforward introduction to one of the most important growth areas in modern medicine.

目次

  • 1. Basic Principles:
  • DNA
  • RNA Structure
  • DNA replication and transcription: it's all the genes
  • Gene expression: making proteins
  • Gene transcription: transmitting the code
  • Translation: reading the code
  • 2.Manipulation of DNA/RNA:
  • Preparation of nucleic acid
  • Cutting and pasting DNA (restriction enzymes and ligases)
  • Extending and chewing DNA (polymerases and nucleases)
  • Making RNA from DNA and vice versa: RNA Pol and reverse transcriptase
  • 3. Molecular techniques:
  • Blotting
  • Hybridization
  • Transfection and transformation: selection and screening
  • DNA analysis
  • RNA analysis
  • Nucleic acid-protein interactions
  • Transgenic animals (adding genes)
  • Knockout animals (deleting genes)
  • 4. Understanding genetics:
  • Evolution of the human genome
  • Inheriting genes
  • Diversity in the genome: why are we different? Identifying genetic differences between individuals
  • Finding genes
  • 5. Molecular medicine in practice:
  • Biotechnology in clinical medicine
  • Index

「Nielsen BookData」 より

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