The treatment of epilepsy

著者

書誌事項

The treatment of epilepsy

edited by Simon D. Shorvon ... [et al.] ; foreword by Edward H. Reynolds

Blackwell Science, c1996

大学図書館所蔵 件 / 全12件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This aims to be the definitive textbook and a practical clinical reference on medical and surgical treatment of epilepsy, one of the commonest serious neurological conditions affecting 50 million people worldwide. It forms a detailed review and distillation of the literature, providing answers to the diversity of questions encountered in day to day clinical practice, and guiding the clinician through the difficult decision-making processes involved in the successful therapy of this debilitating disease. The text begins with a concise summary of the recent scientific developments in epileptology and discussion of the classification and diagnosis of epilepsy. A large medical section follows, covering in detail the indications, clinical pharmacology, pharmacokinetics, toxicity and outcome of drug treatment. The surgical section deals with indications, patient selection, pre-surgical assessment, surgical technique, anaesthesia, complications and outcome. Epilepsy is the commonest serious neurological condition and affects 50 million people worldwide. Each day in the UK alone 65 people will suffer their first attack. The chance of developing epilepsy at some point in life has been estimated as high as 3.5% (1 in 30). In most cases it is a chronic condition requiring long-term medical treatment and the affected individual is considerably handicapped despite bearing no outward signs of disability. The successful treatment of epilepsy is a complex process involving careful and rational analysis of a large number of variables and is rarely achieved. In recent years, there have been rapid advances both in medical and surgical

目次

  • Section 1: Principles:
  • The Pathophysiology of Seizure Generation
  • The Developmental Basis of Epilepsy
  • Classification of Epileptic Seizures and the Epilepsies
  • Definitions, Aetiologies and Diagnosis of Epilepsy
  • The Prognosis of Epilepsy
  • The Economic Cost of Epilepsy
  • Section 2: Medical Treatment:
  • Mechanisms of Action of Antiepileptic drugs: An Overview
  • Pharmacokinetic Principles of Drug Treatment
  • Principles of Drug Treatment
  • Principles of Treatment of Newly Diagnosed Patients
  • Principles of Treatment of Patients with Chronic Active Epilepsy
  • Treatment of Patients with Epilepsy in Remission
  • Treatment of the Childhood Epilepsy Syndromes
  • Treatment of Epilepsy in Children and Adults with Multiple Handicaps
  • Treatment of Epilepsy in the Elderly Patient
  • Treatment of the Idiopathic (Primary) Generalized Epilepsies
  • Treatment of Epilepsies with Myoclonias
  • Status Epilepticus: A Proposed Pathophysiology
  • Treatment of Status Epilepticus and Serial Seizures
  • Treatment of Epilepsy in General Medical Conditions
  • Drug Interactions Involving Antiepileptic Drugs
  • Reproductive Aspects of Epilepsy Treatment
  • Genetic Counselling in Epilepsy and Teratogenesis
  • Psychiatric Disorders in Epilepsy
  • Non-Pharmacological Treatments of Epilepsy
  • Social Issues in Epilepsy
  • Section 3: Antiepileptic Drugs:
  • Clobazam
  • Clonazepam
  • Other Benzodiazepines
  • Carbamazepine and Oxcarbazepine
  • Ethosuximide and Methsuximide
  • Felbamate
  • Gabapentin
  • Lamotrigine
  • Phenobarbitone
  • Phenytoin
  • Piracetam
  • Topiramate
  • Valproate
  • Vigabatrin
  • Other Drugs Used in the Treatment of Epilepsy
  • Antiepileptic Drugs in Clinical Trials
  • Section 4: Surgical Treatment:
  • Principles of Epilepsy Surgery
  • Clinical Localization: Conceptual Problems and Pitfalls
  • The Role of Scalp Electroencephalography in Presurgical Evaluation
  • Invasive Electroencephalography Evaluation for Epilepsy Surgery
  • Magnetic Resonance Imaging Evaluation for Epilepsy Surgery
  • Positron Emission Tomography and Single-Photon Emission Computed Tomography in the Non-Invasive Evaluation of Epilepsy
  • Psychological Evaluation for Epilepsy Surgery
  • Psychiatric Evaluation for Epilepsy Surgery
  • Surgery of Neoplastic, Vascular and Infective Mass Lesions
  • Surgery of Congenital, Traumatic and Infectious Lesions and those of Uncertain Aetiologies
  • Surgery of Mesial Temporal Epilepsy
  • Paediatric Epilepsy Surgery
  • Hemispherectomy
  • Corpus Callosum Section
  • Multiple Subpial Transection
  • Awake Operations
  • Stereotactic Neurosurgery for Epilepsy
  • Reoperation in Surgical Failures
  • Complications of Epilepsy Surgery
  • Anaesthesia in Epilepsy Surgery
  • Challenges for Epilepsy Surgery
  • Index

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