Neurobiology of Alzheimer's disease
著者
書誌事項
Neurobiology of Alzheimer's disease
（The molecular and cellular neurobiology series）
Bios Scientific, 1995
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注記
Includes bibliographies and index
内容説明・目次
内容説明
Several major advances have been made recently in understanding the aetiology of Alzheimer's disease. This volume contains up-to-date reviews on current key issues relating to both the aetiology and treatment of the disease. Topics covered range from molecular neuropathology through diagnostic and clinical aspects, with both immediate and long-term therapeutic solutions. In-depth analyses are given of the molecular nature of amyloid and tau proteins, the genetics of familial Alzheimer's disease, the role of apolipoprotein E and the use of transgenic models. The neurochemistry of the disease is also discussed, highlighting potential areas for pharmacological intervention.
目次
1: S J Allen & Dawbarn: Alzheimer's disease: current controversies - an overview. 2: D R Howlett, S James, D Allsop and G W Roberts: The biology and molecular pathology of (-amyloid protein. 3: W Wasco and R E Tanzi: Molecular genetics of amyloid and apolipoprotein E in Alzheimer's disease. 4: J Hardy: Genetics of Alzheimer's disease: age of onset as a key discriminator of etiology. 5: C Wischik, P C Edwards and C R Harrington: The tau protein amyloidosis of Alzheimer's disease: its mechanisms, potential trigger factors and consequences. 6: M J Savage, D S Howland, S M Ali, S Siedlak, G Perry, R Siman, R W Scott and B D Greenberg: APP transgenesis: approaches towards the development of animal models for Alzheimer's disease neuropathology. 7: A W Procter, P T Francis, C P L -H Chen, I P Chessell, S Dijk, N A Clarke, M -T Webster and D M Brown: The neurochemical pathology of Alzheimer's disease. 8: H F Baker & R M Ridley: Cholinergic grafts in primates. 9: J Treanor, K Beck, & F Hefti: Neuronal growth factors and Alzheimer's disease. 10: N Fox, P Hartikainen and M Rossor: Alzheimer's disease and structural imaging: CT and MRI. 11: G K Wilcock: Pharmacological approaches to treating Alzheimer's disease
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