書誌事項

Interleukin-10

[edited by] Jan E. De Vries, René de Waal Malefyt

(Molecular biology intelligence unit)

R.G. Landes, c1995

この図書・雑誌をさがす
注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book examines the structure and the in vitro and in vivo biological characterization of a recently discovered cytokine: interleukin - 10 (IL-10). The information collected in this volume is a state-of-the-art summary of the pleiotropic effects of IL-10 in vitro and in vivo and significantly contributes to our understanding of the role of IL-10 in the immune system and its potential clinical utility in the near future. Section 1: describes the characterization of the structure of the IL-1O cDNAs, IL-10 genes, IL-1O proteins and IL-10 receptors. Section 2 reviews the in vitro biological effects of IL-10 on both mouse and human lymphoid as well as myeloid cells. Includes discussions regarding the role of IL-10 in transplantation, parasite infections, inflammation, infectious diseases and bone formation. Section 3 examines the effects of IL-1O in vivo and the capacity of IL-10 to prevent lethal toxic shock in mice.

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