Percutaneous penetration enhacers

著者

• Smith, Eric W.
• Maibach, Howard I.

書誌事項

Percutaneous penetration enhacers

edited by Eric W. Smith, Howard I. Maibach

CRC Press, c1995

注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book is a comprehensive reference on the methods available for the enhancement of percutaneous penetration. It examines a broad scope of chemical enhancers and various physical methods of enhancement. The range of chemicals discussed in this volume is unsurpassed anywhere in the literature. Scientists can find invaluable information in this single source on 95 percent of the enhancers being researched today! Each well-illustrated chapter is written by the world's leading authorities in the field. Introductory chapters outline the concept of penetration enhancement from first principles and provide a comprehensive classification of different types of enhancers.Chapters covering chemical enhancers are clear, concise, and easy to understand, even for novice readers in this field. The latest techniques by which drugs can be forced physically through the skin are also covered in depth. Equipment is detailed, typical drug candidates for the techniques are described, and the success to date is provided. Percutaneous Penetration Enhancers is the first book to present modern analytical techniques that have been used to assess penetration enhancement. The book also offers future perspectives for enhancers. New approaches and current limitations on knowledge and understanding of the topic are suggested. This timely source book is invaluable for clinical reference or for the design of scientific studies.

目次

Percutaneous Penetration Enhancers: The Fundamentals, E.W. Smith and H.I. Maibach Penetration Enhancer Classification, S. Chattaraj and R.B. Walker Penetration Enhancement by Skin Hydration, R.C. Wester and H.I. Maibach Effect of Hydration on Corticosteroid Absorption, J.M. Haigh and E.W. Smith Use of Occluding Hydrocolloid Patches, D.A. Hollingsbee, R.J. White, and P.A.D. Edwardson Alcohols, B. Berner and P. Liu Propylene Glycol, B. Bendas and R. Neubert Amines and Amides as Penetration Enhancers, B.B. Michniak Alkyl N,N-Disubstituted-Amino Acetates, N. Buyuktimkin, S. Buyuktimkin, and J.H. Rytting Decylmethylsulfoxide, E. Touitou and D. Chow Dimethylsulfoxide, T.J. Franz Penetration Enhancement using Azone, G. Allan Human Stratum Corneum Barrier Impairment by N-Alkyl-Azacycloheptanones, J.A. Bouwstra and H.E. Bodde Enhanced Percutaneous Absorption of Azone following Single and Multiple Doses to Human Volunteers, R.C. Wester and H.I. Maibach Metabolism of the Penetration Enhancer Azone: In Vivo and In Vitro Studies in the Hamster, Rat, Monkey, and Man, J.W. Wiechers Azone Analogues as Penetration Enhancers, B.B. Michniak Interaction of Azone with Model Lipid Systems, G. Lee Pyrrolidones as Penetration Enhancers, H. Sasaki, K. Nishida, and J. Nakamura Drug-Polyvinylpyrrolidone Co-precipitates, O.I. Corrigan Profile of Pirotiodecane (HPE-101): A New Potential Penetration Enhancer, T. Yano, Y. Shimozono, T. Manako, K. Fukuda, S. Yahiro, and K. Noda Surfactants, S. Ruddy Benzalkonium Chloride Polymers, T. Aoyagi and Y. Nagase Silicone-Based Polymers, T. Aoyagi and Y. Nagase Fatty Acids as Skin Permeation Enhancers, B.J. Aungst Urea and Its Derivatives as Penetration Enhancers, A.C. Williams Biodegradable Unsaturated Cyclic Ureas as Penetration Enhancers, O. Wong and J.H. Rytting Terpenes as Penetration Enhancers, M. Hashida and F. Yamashita Liposomes as Penetration Enhancers and Controlled Release Units, M.-H. Schmid and H.C. Korting The Effect of Cyclodextrins on Percutaneous Transport of Drugs, T. Loftsson and N. Bodor Triple Therapy: Multiple Dosing Enhances Hydrocortisone Absorption In Vivo in Man, R.C. Wester, J. Melendres, F. Logan, and H.I. Maibach Iontophoresis, B.H. Sage Ultrasound, E. Camel Delipidization of the Cutaneous Permeability Barrier and Percutaneous Penetration, E. Menczel Electroporation, M.R. Prausnitz, V.G. Bose, R. Langer, and J.C. Weaver The Use of Ion Pairing to Facilitate the Percutaneous Absorption of Drugs, S. Matschiner, R. Neubert, and W. Wohlrab Raman Spectroscopy, A.C. Williams and B.W. Barry Electron Spin Resonance, D. Quan and H.I. Maibach X-Ray Fluorescence, J.D. Robertson and M. Jay Assessing Penetration Enhancers for Corticosteroids, E.W. Smith and J.M. Haigh Fluorescence Spectroscopy, W. Abraham Some New Approaches to Understanding and Facilitating Transdermal Drug Delivery, P.S. Magee Future Perspectives for Penetration Enhancers, E.W. Smith and H.I. Maibach

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詳細情報

• NII書誌ID(NCID): BA27209676
• ISBN:
  • 0849326052
• LCCN: 95007119
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Boca Raton ; Tokyo
• ページ数/冊数: 500 p.
• 大きさ: 24 cm
• 分類:
  • LCC : RM151
  • DC20 : 615/.6
• 件名:
  • LCSH : Transdermal medication
  • LCSH : Skin absorption