Gene expression : general and cell-type-specific
著者
書誌事項
Gene expression : general and cell-type-specific
（Progress in gene expression）
Birkhäuser, c1993
- :
- :
大学図書館所蔵 件 / 全6件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
: ISBN 9780817636050
内容説明
This book is the first volume in a new series Progress in Gene Expres- sion. The control of gene expression is a central-most topic in molecular biology as it deals with the utilization and regulation of gene informa- tion. As we see huge efforts mounting all over the developed world to understand the structure and organization of several complex eukaryotic genomes in the form of Gene Projects and Genome Centers, we have to remember that without understanding the basic mechanisms that gov- ern the use of genetic information, much of this effort will not be very productive. Fortunately, however, research during the past seven years on the mechanisms that control gene expression in eukaryotes has been extremely successful in generating a wealth of information on the basic strategies of transcriptional control. (Although regulation of gene ex- pression is exerted at many different levels, much of the emphasis in this series will be on transcriptional control. A future volume, however, will deal with other levels of regulation). The progress in understanding the control of eukaryotic transcription can only be appreciated by realizing that seven years ago we did not know the primary structure of a single sequence specific transcriptional activator, and those whose primary structures were available (e. g. , homeo- domain proteins) were not yet recognized to function in this capacity.
目次
1. The Basic Transcriptional Machinery.- 2. Plasticity of the Differentiated State.- 3. Gene Regulation by Steroid Hormones.- 4. Control of Transcription and Cellular Proliferation by cAMP.- 5. Transcription Factors Controlling Muscle-Specific Gene Expression.- 6. Gene Expression in Hematopoietic Cells: The ?-Globin Gene.- 7. Transcriptional Control of Gene Expression in Hepatic Cells.- 8. Transcriptional Control of Pituitary Gene Expression.
- 巻冊次
-
: ISBN 9783764336059
内容説明
This exciting collection of review articles provides a comprehensive introduction to this important area of molecular biology - written by the world's top molecular and cellular biologists. Each chapter begins with the basic concepts and progresses to a state-of-the-art review of current literature, making the book invaluable for students entering the field. Seasoned researchers will value the keen insights into related areas, such as immunology, neuroscience, and endocrinology. Topics include: Basic transcription; Cell differentiation and plasticity; Gene regulation by steroid hormones; Cellular proliferation; Muscle-specific gene expression; Gene expression and differentiation in the hematopoietic system; Hepatic gene expression and its regulation; Gene expression and differentiation of neuroendocrine cells. This book is the first in a series covering all aspects of gene expression and regulation, and related areas of molecular biology. It is essential reading for all molecular biologists, cell biologists, biochemists, and biotechnologists.
「Nielsen BookData」 より