T-cell subsets and cytokines interplay in infectious diseases : international conference, Kuwait, April 6-8, 1993
著者
書誌事項
T-cell subsets and cytokines interplay in infectious diseases : international conference, Kuwait, April 6-8, 1993
Karger, c1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Presenting a wealth of new data on the interaction among t-cell subsets and cytokines, this book offers a fresh perspective on infectious diseases. It provides useful insights into the nature and treatment of helminthic and mycobacterial infections, with special emphasis on leprosy, leishmaniasis, malaria and trypanosomiasis. The outcome of the host response to infectious agents is seen as depending upon the t-cell subsets activated and the cytokines produced by them and other cells, such as macrophages, beta-cells and basophils. Expert contributions shed new light on: how THO cells are preferentially activated and differentiated into TH1 or TH2 subsets; how TH1 and TH2 cells and their cytokines induce both protective immune responses and adverse immune reactions to infectious agents; how cytokines modulate the response of infectious diseases to chemotherapy; and how cytokines, their receptors and antagonists, and anti-cytokine antibodies can be used in therapy. Those working in the fields of immunology, parasitology, microbiology and vaccine development, particularly if they are interested in tropical diseases, should find the volume a valuable source of information.
目次
- Part 1 Regulation and activation of t-cell subsets: tolerance-of-self and protection against autoimmunity, A. Mitchison et al
- human TH1 and TH2 cells - functional properties, regulation of development and role in disease, G. Del Prete and S. Romagnani
- t-cell functions in tuberculosis, J. Ivani
- subsets of human gammadelta lymphocytes, D. Kabelitz et al
- can universally efficacious vaccination be developed against "leishmania major" and other pathogens uniquely susceptible to cell-mediated attack?, P.A. Bretscher. Part 2 Role of t-cell subsets and cytokines in malaria: t-cell subsets and effector mechanisms of pathology in cerebral malaria, G.E. Grau
- the role of cytokines and nitric oxide against leishmania and malaria infection, F.Y. Liew. Part 3 Role of t-cell subsets and cytokines in leishmaniasis: the skin immune system across the spectrum of American cutaneous leishmaniasis - t-cell subsets and cytokine production, F.J. Tapia et al
- type 1 and type 2 cytokine expression in human American mucocutaneous leishmaniasis, C. Pirmez and R.L. Modlin
- some aspects of the t-cell responses elicited during infection of mice with "leishmania major", J.A. Louis
- differentiation of CD4+ t-helper-cell subsets in leishmaniasis, P. Scott
- modulation of host macrophage responses in "leishmania" and host t-cell responses to recombinant "leishmania" antigens, W.R. McMaster and N.E. Reiner. Part 4 Role of t-cell subsets and cytokines in trypanosomiasis: mechanisms underlying trypanosome-induced t-cell immunosuppression, P. De Baetselier. Part 5 Role of t-cell subsets and cytokines in helminthic infections: lung phase immunity in the blood fluke "schistosoma mansoni" - the role of cytokines in the protective response of mice, R.A. Wilson
- t-cell activation and antibody responses in lymphatic filariasis, M. Yazdandakhsh et al. Part 6 Role of t-cell subsets and cytokines in mycobacterial infections: the interplay between cytokines and t-cells in immunity to intracellular bacteria, S.H.E. Kaufmann
- immunoregulation and cytokine patterns in leprosy, P. Salgame and B.R. Bloom
- the role of cytokines in leprosy, I. Nath et al
- recombinant mycobacterial antigens and epitopes recognized by human t-cells, A.S. Mustafa. Part7 Overview: t-cell subsets and cytokines interplay in infectious diseases - an overview, A.S. Mustafa.
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