CiNii Books - Regulation of cardiac function : molecular, cellular and pathophysiological aspects

This book gives a consensus of views and research trends in the regulation of cardiac function and metabolism. Emphasis is given to the elucidation of fundamental concepts and principles of clinically relevant issues. The aim is that the clinician should be able to approach a particular aspect of any given problem logically, thereby gaining insights into the fundamental pathophysiological mechanism underlying diseases states. Regulation of Cardiac Function is organized within six principle areas from the molecular and cellular aspects to more clinically applied problems of heart disease. This book gives pertinent guidelines and summarizes knowledge on basic research relevant to cardiac function and metabolism in health and disease.

Table of Contents

Preface Introduction CHAPTER 1: CARDIAC CONTRACTILE PROTEINS AND EXCITATION CONTRACTION COUPLING Excitation-contraction coupling and Ca2+ Arnold M. Katz Involvement of the sarcolemmal membrane in cardiac contraction and relaxation N.S. Dhalla Ionic mechanisms and their regulation in cardiac excitation M. Hiraoka Control of Ca ion by the cardiac sarcoplasmic reticulum M. Endo Contractile mechanisms of heart muscle I. Matsubara Regulation of cardiac function cardiac myosin isozymes: a molecular and cellular study Y. Yazaki CHAPTER 2: ULTRASTRUCTURE OF THE MYOCARDIUM Ultrastructure and function of the myocardium V.J. Ferrans Architecture of hypertrophied myocardium: scanning and transmission electron microscopy K. Kawamura Myocardial ultrastructure in cardiomyopathic animals H. Tanaka Histology of the human conduction system R. Okada CHAPTER 3: ISCHEMIC HEART AND ENERGY METABOLISM Role of metabolism on ischaemia L.H. Opie Energy metabolism in ischemic myocardium: NMR study S. Imai Cardiac oxygen metabolism M. Tamura The role of phospholipase in mitochondrial dysfunction after coronary reperfusion T. Ozawa Role of L-carnitine in ischemic heart disease N. Yamazaki CHAPTER 4: PUMP FUNCTION IN NORMAL AND FAILING HEART Heterogeneous transmural blood flow and microvascular spasm as causes of heart failure in ischemic heart disease and cardiomyopathies E.H. Sonnenblick Dynamic property of ventricular relaxation M. Hori Contractile state of the hypertrophied ventricle S. Sasayama Diastolic performances of ischemic left ventricle M. Iizuka CHAPTER 5: CORONARY VASOPLASM AND THROMBOSIS Thrombosis, platelets and coronary atherosclerosis K. Tanaka Mechanism of vasospasm and thrombosis in coronary artery disease: altered metabolism of thromboxane A2 and prostaglandin I2 M. Tada Prostaglandin and blood vessel function N. Toda Coronary artery spasm in experimental animals M. Nakamura CHAPTER 6: CARDIOVASCULAR PHARMACOLOGY The cultured myocardial cell as a model in heart research A. Wollenberger The mechanism of beta-adrenergic stimulation of adenylate cyclase in the heart P. Harris Profiles of new positive inotropic drugs N. Taira Efficacies of antianginal drugs in relation to pathophysiology of angina pectoris H. Fukuzaki Functions of the specialized conducting system and their regulation Y. Watanabe Subject index

by "Nielsen BookData"

Regulation of cardiac function : molecular, cellular and pathophysiological aspects

Author(s)

Bibliographic Information

Available at 3 libraries

Search this Book/Journal

Note

Description and Table of Contents

Details

Export