Cyclodextrins in pharmacy
著者
書誌事項
Cyclodextrins in pharmacy
（Topics in inclusion science, v. 5）
Kluwer Academic Publishers, c1994
- acid-free paper
- : [pbk.]
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注記
Publishers name varies: Springer-Science+Business Media, B.V.
Includes bibliographical references and index
内容説明・目次
内容説明
Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems.
The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation.
This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.
目次
- Preface. Introduction: Historical Developments
- Cyclodextrins and their Effects on Drugs. 1. Cyclodextrins. 2. CD Derivatives. 3. Interaction between CDs and Biological Systems. 4. Interaction between Drugs and CDs in Aqueous Systems. 5. Interaction between Drugs and CDs in Solid State. 6. Preparations of Cyclodextrin Inclusion Compounds. 7. CDs in Various Drug Formulations. 8. Stabilization of Drugs. 9. Pharmacokinetical and Biopharmaceutical Consequences of Complexation. 10. Various Pharmaceutical Applications. 11. Pharmaceutical-Technological Aspects of CDs in the Drug Formulation. 12. CD-Complexed Drugs. 13. Legal Aspects. References. Index.
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