Th1 and Th2 cells in health and disease
著者
書誌事項
Th1 and Th2 cells in health and disease
（Chemical immunology, v. 63）
Karger, c1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Th1 and Th2 cells, representing extremely polarized modalities of the specific effector immune response, play an important role in both protection against exogenous insults and the induction of several immunopathological reactions. This book provides an authoritative update on the developments in this fast-moving field from both basic and clinical perspectives. In 12 detailed chapters, leading immunologists highlight the physiological meaning of Th1 and Th2 cells, their functional properties and surface markers, the mechanisms responsible for their development, as well as their roles in protection against bacteria, protozoans, fungi, viruses and helminths. Also discussed are the roles of Th1 and Th2 cells in some immunopathological conditions, such as autoimmune and neurological disorders, allergy and HIV infection. By combining for the first time complete information on basic mechanisms together with the clinical implications of Th1/Th2-dominated immune responses, this book will be appreciated by a broad spectrum of readers, including immunobiologists and clinicians from many medical fields.
目次
- Role of cytokines in development of Th1 and Th2 cells, A. O'Garra and K. Murphy
- role of interleukin-12 in human Th1 response, G. Trinchieri
- markers of Th1 and Th2 cells, F. Almerogogna et al
- initiation and regulation of CD4+ t-cell function in host-parasite models, D. Jankovic and A. Sher
- role of Th1 and Th2 cells in bacterial infections, S. Daugelat and S.H.E. Kaufmann
- Th cell development and regulation in experimental cutaneous leishmaniasis, P. Scott
- biological role of Th cell subsets in candidiasis, L. Romani et al
- Th1 and Th2 cells in HIV infection, R. Manetti et al
- Th1 and Th2 cells in autoimmunity, P. Druet et al
- role of Th1 and Th2 cells in neurologic disorders, A. Windhagen et al
- role of Th1 and Th2 cells in human allergic disorders, D.S. Robinson and A.B. Kay
- molecular and biological characteristics of interleukin-13, J.E. de Vries.
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