Functions and biogenesis of peroxisomes in relation to human disease

書誌事項

Functions and biogenesis of peroxisomes in relation to human disease

edited by R.J.A. Wanders, R.B.H. Schutgens and H.F. Tabak

(Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede reeks ; deel 95)

North-Holland, 1995

タイトル別名

"Proceedings of the colloquium, Amsterdam, 18-19 October 1993" - half title

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注記

Includes bibliographical references

内容説明・目次

内容説明

Perixisomes have attracted great interest in recent years since it was recognized that impairments in one or more peroxisomal functions are associated with severe disease. This book aims to describe the current state of knowledge about peroxisomes concentrating on the functions and biogenesis of peroxisomes with special emphasis on the various peroxisomal disorders. Accordingly, this book contains chapters on the functions of peroxisomes (fatty acid oxidation, ether-phospholipid synthesis, cholesterol synthesis), the biogenesis of peroxisomes and chapters dealing with the (dys)functions and morphology of peroxisomes in the various peroxisomal disorders.

目次

  • Functional aspects of peroxisomal B-oxidation: an overview, G.P. Nannaerts, P.P. van Veldhoven
  • Peroxisomal Boxidation: enzymological and molecular biological aspects, T. Hashimoto
  • Localization of cholesterol synthesis enzymes in peroxisomes, S.K. Krisans
  • Ether phospholipid biosynthesis: and overview, H. van den Bosch et al
  • Functions for ether phospholipids in animal cells, R.A. Zoeller
  • Peroxisomal protein import, W.W. Just et al
  • Biogenesis and function of peroxisomes in hansenula polyforma, I.J. van de Klei, M.E. Evers, M. Veenhuis
  • Comparative studies on peroxisome biogenesis in s. cerevisiae and human fibroblasts, H.F. Tabak et al
  • Ppars: nuclear hormone receptors controlling peroxisomal fatty acid B-oxidation, G. Krey et al
  • Disorders of peroxisome biogenesis: classification and treatment, P.G. Barth et al
  • The many faces of X-linked adrenoleukodystrophy: implications for pathogenesis and the evaluation of therapy, H.W. Moser et al
  • Deletion of the acyl-coA oxidase gene in isolated acyl-CoA oxidase deficiency (pseudo-neonatal adrenoleukodystrophy), B.T, Poll-The et al
  • identification of the genetic defect in X-linked adrenoleukodystrophy, P. Aubourg, J.L. Mandel
  • Cell and tissue heterogeneity in peroxisomal patients, F. Roels et al.

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