Clinical diagnosis and management by laboratory methods
著者
書誌事項
Clinical diagnosis and management by laboratory methods
Saunders, c1996
19th ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This text provides integrated scientific guidance for diagnosis and clinical management, as well as disease prevention and health promotion. The focus is on medical and laboratory problem-solving, assessing the merits of each blood or body fluid measurement, examination or determination in terms of sensitivity, specificity, precision, and accuracy. Features include: material on oncology, covering cell biology and early tumour detection, including diagnosis and management of cancer using tumour markers as well as PCR and oncogenes in the early detection and management of cancer; a section on molecular pathology, featuring topics such as basic principles and techniques, establishing a molecular diagnostics laboratory, molecular diagnosis and pathology of infectious diseases, genetic diseases, and haematopoietic neoplasms; and information on immunology and immunopathology, including cytokines and adhesion molecules, MHC and disease, vascular inflammatory, rheumatic, autoimmune, and allergic diseases. The text aims to enable the reader to develop a clear understanding of the order and sequence of lab tests, as well as the interpretation of results.
目次
- Part 1 The clinical laboratory: the clinical laboratory: organization, purposes and practice
- physician office laboratories
- principles of instrumentation
- interpreting laboratory results: reference values and decision making
- informatics, imaging and the pathologist's workstation
- quality management. Part 2 Clinical chemistry: evaluation of renal function, water, electrolytes, acid-base balance, and blood gases
- metabolic intermediates and inorganic ions
- carbohydrates
- lipids and dyslipoproteinemia
- specific proteins
- assessment of liver function
- clinical enzymology
- polymerise chain reaction in early detection and monitoring of cancer
- cell biology and early tumour detection
- evaluation of endocrine function
- toxicology and therapeutic drug monitoring. Part 3 Urine and other body fluids: basic examination of urine
- cerebrospinal, synovial, and serous body fluids
- clinical application of human chorionic gonadotropin
- examination of amniotic fluid
- andrology laboratory and fertility assessment
- laboratory diagnosis of gastrointestinal tract and exocrine pancreatic disorders. Part 4 Haematology, coagulation, and transfusion medicine: basic examination of blood
- haematopoiesis
- erythrocytic disorders
- leucocytic disorders
- blood platelets
- blood coagulation and fibrinolysis
- immunohematology
- transfusion medicine. Part 5 Immunology and immunopathology: overview of the immune system
- immunoassays and immunochemistry
- laboratory evaluation of the cellular immune system
- laboratory evaluation of immunoglobulin function and humeral immunity
- complement and kinins: mediators of inflammation
- cytokines and cell adhesion molecules
- human leucocyte antigen (HLA): the major histocompatibility complex of human and transplantation immunology
- the major histocompatibility complex and disease
- immunodeficiency disorders
- clinical and laboratory evaluation of systemic rheumatic diseases
- vasculitis
- organ-directed autoimmune diseases
- allergic diseases
- diagnosis and management of cancer using serologic tumour markers. Part 6 Medical microbiology: viral infections
- chlamydial, rickettsial and mycoplasmal infections
- medical bacteriology
- in vitro testing of antimicrobial agents
- spirochaete infections
- micobacteria
- mycotic diseases
- medical parasitology
- specimen collection and handling for diagnosis of infectious diseases. Part 7 Molecular pathology: molecular pathology: an introduction
- molecular diagnostics: basic principles and techniques
- establishing a molecular diagnostic laboratory
- molecular genetics of haematopoietic neoplasm. (Part contents).
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