Development and applications of vaccines and gene therapy in AIDS

書誌事項

Development and applications of vaccines and gene therapy in AIDS

volume editors, G. Giraldo ... [et al.]

(Antibiotics and chemotherapy, vol. 48)

Karger, c1996

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注記

"International workshop, Naples, June 15-16, 1995."

Includes bibliographical references and index

内容説明・目次

内容説明

This publication is an overview of the exciting discoveries in the field of AIDS which were discussed at the workshop 'Development and Applications of Vaccines and Gene Therapy in AIDS' (Naples, June 1995). Various articles present the latest advances in the development of vaccines, focusing on the analysis of immunogenetic epitopes and models of expression and/or administration. Some contributions describe the results of recent vaccine trials with animal models while others concentrate on human clinical trials. Furthermore, articles on new approaches in the field of gene therapy are included. The data compiled in this outstanding volume is essential not only for biomedical scientists but also for all researchers interested in the latest developments in the field of HIV/AIDS.

目次

  • Importance of collaboration between research and public health institutions from developing and industrialized nations in the development of efficient preventive measures for AIDS, particularly through vaccines, J.G.S. Makumbi
  • Immunologic responses in AIDS: Host factors in the pathogenesis of HIV disease, A.S. Fauci
  • Questions about CD8+ anti-HIV lymphocytes in the control of HIV infection, J.P. Levy
  • Mucosal receptors and T-and B-cell imuunity, T. Lehner et al. Vaccine development I - immunogenic epitope analysis: Genetic variability: implications for the development of HIV vaccines, S. Osmanov et al
  • Region genotyping of HIV isolates in northern Uganda: heteroduplex mobility assay, nucleotide sequence and phylogenetic analysis, F.M. Buonaguro et al
  • HIV-1 biological phenotype varies with severity of infection across HIV-1 genetic subtypes, E.M. Fenyo
  • Immunotyping HIV-1 in the 1960s, P.L. Nara. Vaccine development II - models of expression and/or administration: Overview of HIV vaccine development, D.P. Bolognesi
  • Requirements for testing of an antigenetically expanded Pr55gag-based HIV candidate vaccine in a field study, R. Wagner et al
  • Role of adjuvants in HIV vaccine design, F.R. Vogel
  • Relative importance and functional role of genetic elements targeted for a live attenuated AIDS vaccine, S.M. Lang, R.C. Desrosiers
  • Vaccination of mice and nonhuman primates using HIV gene-containing DNA, M.A. Liu et al
  • Immune responses to the HIV rev regulatory gene, B. Wahren et al. Animal methods: Vaccine trials in cynomolgus monkeys, G. Biberfeld et al
  • Vaccination of chimpanzees against HIV-1, M. Girard et al
  • Evaluation of protective immunity to HIV-1 in human PBL-SCID mice, D.E. Mosier
  • Vaccination of cynomolgus monkeys with whole inactivated or live-attenuated simian immunodefiency virus, F. Titti et al. Human clinical trials of HIV vaccines: Establishment of WHO-sponsored field sites for HIV vaccine evaluation in developing countries, W.L. Heyward et al
  • Combination strategies for vaccination against HIV, S.A. Plotkin
  • Immunological aspects of patients with HIV-1 disease following immunization with recombinant gp160(VaxSyn), E. Guerra et al
  • Preparation for HIV vaccine efficacy trials, R. Hoff, D.N. Lawrence
  • Strategies for achievement of prophylactic vaccination against HIV, M.R. Hilleman. Passive immunotherapy in HIV infection: Conformation of the HIV-1 gp120 envelope glycoprotein, J. Sodrosky et al. Gene therapy in HIV: Some novel approaches to the control of HIV and select aspects of HIV pathogenesis, R.C. Gallo
  • TAR decoys and trans-dominant gag mutant for HIV-1 gene therapy, J. Lisziewicz
  • Genetic pharmacomodulation of nucleoside analogue and gene therapy for Aids and cancer, N. Guettari et al. (Part contents).

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