Pharmaceutical powder compaction technology
Author(s)
Bibliographic Information
Pharmaceutical powder compaction technology
(Drugs and the pharmaceutical sciences, v. 71)
M. Dekker, c1996
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Note
Includes index
Description and Table of Contents
Description
This unique reference examines the modern pharmaceutical compacting techniques used to form tablets out of powders-describing the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles.
Table of Contents
Interparticulate Bonding Characteristics of Pharmaceutical Compacts
Interparticulate Attraction Mechanisms, Claus Fuhrer
The Importance of Intermolecular Bonding Forces and the Concept of Bonding Surface Area, Christer Nystroem and Per-Gunnar Karehill
Characterization of the Compression Process
Porosity-Pressure Functions, Petteri Paronen and Jukka Ilkka
Force-Displacement and Network Measurements, Gert Ragnarsson
Viscoelastic Models, Fritz Muller
Application of Percolation Theory and Fractal Geometry to Tablet Compaction, Hans Leuenberger, Ruth Leu, and Jean-Daniel Bonny
Characterization of Compact Properties
Mechanical Strength, Peter N. Davies and J. Michael Newton
Tablet Surface Area, N. Anthony Armstrong
Rationale for and the Measurement of Tableting Indices, Everett N. Hiestand
Material Properties of Importance for Powder Volume Reduction and Compact Strength
Particle Dimensions, Goeran Alderborn
Mechanical Properties, Ray C. Rowe and Ron J. Roberts
Granule Properties, Goeran Alderborn and Martin Wikberg
Modeling the Compression Behavior of Particle Assemblies from the Mechanical Properties of Individual Particles, Wendy C. Duncan-Hewitt
Compaction Properties of Excipients and Powder Mixtures
Materials for Direct Compaction, Gerald K. Bolhuis and Zak T. Chowhan
Compaction Properties of Binary Mixtures, John T. Fell
Lubricant Sensitivity, Gerad K. Bolhuis and Arne W. Hoelzer
The Development and Optimization of Tablet Formulations Using Mathematical Methods, Fridrun Podczeck
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