Oral mucosal drug delivery

書誌事項

Oral mucosal drug delivery

edited by Michael J. Rathbone

(Drugs and the pharmaceutical sciences, 74)

Marcel Dekker, c1996

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注記

Includes indexes

内容説明・目次

内容説明

Offering comprehensive coverage of the latest developments concerning every important aspect of drug delivery to or via the oral cavity, this state-of-the-art reference examines the problems, limitations, and advantages of the oral cavity as a site for drug delivery, as well as the design, fabrication, optimization, and assessment of a wide range of local and systemic oral mucosal drug delivery systems.

目次

Structure and Function of the Oral Mucosa and Implications for Drug Delivery, Christopher A. Squier and Philip W. Wertz Biochemical Basis of the Permeability Barrier in Skin and Oral Mucosa, Philip W. Wertz, A. Janet Hoogstraate, and Christopher A. Squier Routes of Drug Transport Across Oral Mucosa, Hao Zhang and Joseph R. Robinson Oral Mucosal Permeation Enhancement: Possibilities and Limitations, Bruce J. Aungst In Vitro Methods for Measuring Permeability of the Oral Mucosa, Hao Zhang and Joseph R. Robinson Buccal Epithelial Cell Cultures as a Method to Study Oral Mucosal Drug Transport and Metabolism, Kenneth L. Audus In Vivo Techniques for Studying the Oral Mucosal Absorption Characteristics of Drugs in Animals and Humans, Michael J. Rathbone, Robert Purves, Firoz A. Ghazali, and Ping C. Ho The Flow of Saliva and Its Influence on the Movement Deposition, and Removal of Drugs Administered to the Oral Cavity, John A. Weatherell, Colin Robinson, and Michael J. Rathbone Salivary Mucins: Their Role in Oral Mucosal Barrier Function and Drug Delivery, Leon C. P. M. Schenkels, Tarikere L. Gururaja, and Michael J. Levine Mucoadhesive Hydrogels for Buccal Delivery, Ian W. Kellaway and Simon J. Warren Systemic Oral Mucosal Drug Delivery and Delivery Systems, Michael J. Rathbone, Gilles Ponchel, and Firoz A. Ghazali Specialized Oral Mucosal Drug Delivery Systems: Patches, Gary DeGrande, Luce Benes, Francoise Horriere, Herve Karsenty, Claire Lacoste, Roy McQuinn, Jian-Hwa Guo, and Robert Scherrer Specialized Oral Mucosal Drug Delivery Systems: Chewing Gum, Margrethe R. Rassing Intra-Periodontal Pocket Drug Delivery Systems, W. Aubrey Soskolone and Michael Freidman The Intraoral Delivery of Fluoride, Bernadette K. Drummond and John C. Rodda

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