Peritoneal carcinomatosis

書誌事項

Peritoneal carcinomatosis

edited by Paul H. Sugarbaker

(Cancer treatment and research, v. 81-82)

Kluwer Academic Publishers, c1996

  • v. 1 : acid-free paper
  • v. 2 : acid-free paper

大学図書館所蔵 件 / 4

この図書・雑誌をさがす

注記

Includes bibliographical references and index

収録内容

  • [1] Drugs and diseases
  • [2] Principles of management

内容説明・目次

巻冊次

v. 1 : acid-free paper ISBN 9780792337263

内容説明

Peritoneal carcinomatosis dominates the clinical picture of many patients with gastrointestinal, gynecological and urological cancers. For many of them its dev astating effects contribute directly to their death. Most clinicians consider peritoneal carcinomatosis an incurable metastatic disease and give palliative treatment, re stricted to limited surgery and systemic chemotherapy. Contrary to this view, Paul Sugarbaker and his collegues base their approach on the concept that peritoneal carcinomatosis represents regional tumor spread, similar in its impact on treatment and prognosis to that of lymph node metastases in other malignancies. This concept emphasises the value of regional tumor control, as a potentially curative measure. In this book the combination of aggressive cytoreduction and intraperitoneal chemotherapy to control peritoneal carcinomatosis is extensively explored. Basic to this approach is the observation that most cancer cells show only relative resistence against commonly available drugs, which can be overcome by a sufficient increase of drug concentrations in tumor tissue. After intraperitoneal delivery, drugs will reach high tissue concentrations in the superficial few cell layers, while plasma concentrations will remain below toxic levels. Patients with only limited residual tumor at the peritoneal surface after cytoreduction may therefore benefit from intraperitoneal chemotherapy.

目次

  • Foreword
  • A. Cohen. Preface
  • P.H. Sugarbaker. Section I: Pharmacology. 1. Intraperitoneal taxol
  • M. Markman. 2. Early postoperative intraperitoneal adriamycin as an adjuvant treatment for visceral and retroperitoneal sarcoma
  • P.H. Sugarbaker. 3. Intraoperative hyperthermic lavage with cisplatin for peritoneal carcinomatosis and sarcomatosis
  • A. Stephens, et al. 4. Intraperitoneal regional chemotherapy with mitoxantrone
  • K. Link, et al. 5. Treatment of peritoneal carcinomatosis by continuous hyperthermic peritoneal perfusion with cisplatin
  • H.R. Alexander, D.L. Fraker. 6. Surgically directed chemotherapy: heated intraperitoneal lavage with mitomycin C
  • V. Fernandez-Trigo, et al. Section II: Disease states. 7. Pathobiology of peritoneal carcinomatosis from ovarian malignancy
  • T.A. Sugarbaker, et al. 8. Complete parietal and visceral peritonectomy of the pelvis for advanced primary and recurrent rectosigmoid cancer
  • P.H. Sugarbaker. 9. Prognostic features for peritoneal carcinomatosis in colorectal and appendiceal cancer patients when treated by cytoreductive surgery and intraperitoneal chemotherapy
  • P.H. Sugarbaker. 10. Pseudomyxoma peritonei
  • P.H. Sugarbaker. 11. Clinical determinants of treatment failures after cytoreductive surgery and intraperitoneal chemotherapy in patients with pseudomyxoma peritonei
  • V. Fernandez-Trigo, et al. 12. Recurrent intraabdominal cancer causing intestinal obstruction: Washington Hospital Center experience with 42 patients managed by surgery and intraperitoneal chemotherapy
  • A.M. Averbach, P.H. Sugarbaker. 13. Peritoneal carcinomatosis: Natural history and rational therapeutic interventions using intraperitoneal chemotherapy
  • P.H. Sugarbaker. 14. Survival time and prevention of side effects of intraperitoneal hyperthermic perfusion with mitomycin c combined with surgery for patients with advanced gastric cancer
  • S. Fujimoto, et al. 15. Intraperitoneal 5-fluoracil and mitomycin c as an adjuvant to resectable gastric cancer: a status report
  • W. Yu. 16. Mechanism and treatment of peritoneal carcinomatosis: Intraperitoneal chemotherapy with mitomycin c bound to carbon particles
  • T. Takahashi, et al. 17. Peritoneal mesothelioma: treatment approach based on natural history
  • A.M. Averbach, P.H. Sugarbaker. Pathology of peritoneal mesothelioma
  • M.E. Kass. Rationale for intraperitoneal chemotherapy in the treatment of adenocarcinoma of the pancreas
  • S.E. Ettinghausen. Heated intraperitoneal mitomycin c infusion treatment for patients with gastric cancer and peritoneal metastasis
  • S. Fujimoto, et al. Peritoneal carcinomatosis from adenocarcinoma of the colon
  • M.E.T. Schellinx, et al.
巻冊次

v. 2 : acid-free paper ISBN 9780792337270

内容説明

Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.

目次

  • Foreword
  • J. Spratt. Preface
  • P.H. Sugarbaker. Section I: General principles. 1. Metastatic inefficiency: intravascular and intraperitoneal implantation of cancer cells
  • L. Weiss. 2. Intraperitoneal immunotherapy of cancer: a review of options for treatment
  • H.H. van Ravenswaay, A.M.M. Eggermont. 3. Pharmacokinetics of the peritoneal-plasma barrier after systematic mitomycin C administration
  • P.H. Sugarbaker, et al. 4. The peritoneal plasma barrier
  • P. Jacquet. 5. Patterns of spread of recurrent intraabdominal sarcoma
  • T.A. Sugarbaker, et al. 6. Observations concerning cancer spread within the peritoneal cavity and concepts supporting an ordered pathophysiology
  • P.H. Sugarbaker. 7. In-vitro pharmacologic rationale for intraperitoneal regional chemotherapy
  • K. Link, et al. 8. Immunotherapy for peritoneal ovarian carcinoma metastasis using ex vivo expanded tumor infiltrating lymphocytes
  • R. Freeman, C.D. Platsoucas. 9. The role of omentum associated lymphoid tissue in the progression of peritoneal carcinomatosis
  • M. Shimotsuma, et al. 10. Cancer cell seeding during abdominal surgery: experimental studies
  • F. Zoetmulder. 11. The Krukenberg syndrome as a natural manifestation of tumor cell entrapment
  • A.M. Averbach, P.H. Sugarbaker. Section II: Techniques. 12. Peritoneal carcinomatosis and radioimmunoguided surgery
  • S. Schneebaum, et al. 13. Diffuse and gross peritoneal carcinomatosis treated by intraperitoneal hyperthermic chemoperfusion
  • F. Kober, et al. 14. Intraperitoneal heated chemotherapy: a promise with problems
  • B. Loggie. 15. Peritonectomy procedures
  • P.H. Sugarbaker. 16. Progressive release of the left colon for a tension free colorectal or coloanal anastomosis
  • P.H. Sugarbaker. 17. Radiology of peritoneal carcinomatosis
  • A. Archer, et al. 18. Methodologic considerations in treatment using intraperitoneal chemotherapy
  • A.M. Averbach, et al. 19. Safety considerations in the use of intraoperative intraperitoneal chemotherapy
  • S. White, et al. 20. Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy
  • P.H. Sugarbaker. 21. The effects of postoperative intraperitoneal chemotherapy on peritoneal wound healing and adhesion formation
  • P. Jacquet, P.H. Sugarbaker. 22. Current status of staging laparoscopy in colorectal and ovarian cancer
  • M.P. Boente, et al. 23. Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis
  • P. Jacquet, P.H. Sugarbaker. 24. Laser-mode electrosurgery
  • P.H. Sugarbaker. 25. Peritoneal access devices for intraperitoneal chemotherapy
  • S.R. Ash.

「Nielsen BookData」 より

関連文献: 1件中  1-1を表示

詳細情報

ページトップへ