Basic pharmacology

著者

• Foster, R. W.
• Boulton, A. J. M. (Andrew James Michael)

書誌事項

Basic pharmacology

Butterworth-Heinemann, 1996

4th ed / editor, R. W. Foster, authors, A. J. M. Boulton ... [et al.]

注記

Previous ed.: 1991

Bibliography: p548-549. - Includes index

内容説明・目次

内容説明

The fourth edition of this well-known pharmacology textbook retains the overall objectives of the first: to present accounts of drug actions and their mechanisms in an inexpensive, compact and up-to-date form. Intended for all those students of medicine and allied health professions who are embarking on the study of pharmacology, the book assumes no prior knowledge of the subject, assuming only a modicum of chemistry, biology and physiology as prerequisites. 'Basic Pharmacology' continues to provide an excellent introductory text for all those who are embarking on the study of pharmacology. Now in its fourth edition, this book has become an established undergraduate text, presenting a large and complicated subject in a comprehensive yet simple and concise manner. The succinct 'lecture notes' style of the text underlines the logical structure of the subject and makes the book easy to use for revision or for reference. Throughout, the emphasis is on principles rather than details, and on understanding rather than memorization. The authors of this book, the pharmacologists and their teaching colleagues of the School of Biological Sciences at Manchester University, have been able to draw on many years of experience both in the teaching and clinical aspects of pharmacology, as well as in laboratory-based and clinical research to produce a book that is both current and relevant to undergraduate studies across the medical and allied health disciplines. Completely revised and updated for the new edition, this book has been designed to help students appreciate the rationale underlying the uses of drugs in therapeutics. Now divided into nine well thought out chapters, each with its own particular pharmacological theme, the fourth edition of 'Basic Pharmacology' should continue to fulfil its established role as an outstanding undergraduate text.

目次

FULL CONTENTS: 1) General Pharmacology: unifying concepts targets of drug action interactions between drugs drug design, development and testing - pre-clinical phase 2) Drug action on peripheral excitable tissues - drugs acting on signalling mechanisms directly related to receptors for the neurotransmitters acetylcholine and noradrenaline: the anatomy and physiology of the efferent peripheral nervous system and its effectors the effector cells innervated by post-ganglionic autonomic neurones: physiological effects caused by nervous activity the pharmacology of acetylcholinergic axons and their terminals the pharmacology of the acetylcholine receptors of skeletal muscle the pharmacology of the acetylcholine receptors of ganglia the pharmacology of the acetylcholine receptors of smooth muscle, cardiac muscle and exocrine glands cholinesterases and their inhibitors noradrenergic neuroeffector transmission as a target of drug action drugs with noradrenergic pre-junctional sites of action drugs that modify the inactivation of noradrenaline agonists at adrenoceptors antagonists at adrenoceptors the adrenal medulla 3) Drug action on peripheral tissues - drugs acting on signalling mechanisms other than those directly related to receptors for neurotransmitters and hormones: local anaesthesia cardiac antidysrhythmic drugs cardiac glycosides blockers of calcium channels openers (activators) of potassium channels methylxanthines nitrates diuretic agents anticoagulant, antiplatelet and fibrinolytic compounds lipid-lowering drugs 4) Endocrine pharmacology: hypothalamopituitary axis gonadotrophins oestrogens, progestogens and androgens the thyroid gland and drugs used in thyroid abnormalities the adrenal cortex and the corticosteroids drugs in diabetes posterior pituitary hormones angiotensin local hormones inflammation 5) Drug action on the central nervous system: chemical transmission in the central nervous system extrapyramidal disorders of movement antidepressant drugs antipsychotic drugs vomiting, emetic and antiemetic agents opioid analgesic agents and their antagonists stimulant and hallucinogenic agents antipyretic analgesic agents the state of consciousness and the general anaesthetic agents 6) Antiparasitic chemotherapy: biochemical selectivity distributional selectivity acquired drug resistance in parasites chemotherapy of metazoal infestations chemotherapy of protozoal infections chemotherapy of fungal infections chemotherapy of bacterial infections chemotherapy of viral infections chemotherapy of malignant neoplasms 7) Drug disposition and metabolism: absorption distribution elimination armacokinetics drug dosage regimens physicochemical groupings of drugs water-soluble drugs drugs with intermediate solubility lipid-soluble drugs acidic drugs basic drugs 8) Clinical pharmacology: introduction to therapy prescribing in special groups legal aspects of prescribing practical problems of compliance with the prescription unwanted effects of drugs allergically determined hypersensitivity to drugs genetically determined adverse effects of drugs - pharmacogenetics developmental toxicity adverse drug interactions abuse of drugs drug design, development and testing - clinical phase 9) Pharmacotherapeutics: the process of rational therapeutics acute poisoning peptic ulceration inflammatory bowel disease gastrointestinal motility disorders congestive heart failure hypertension and antihypertensive drugs angina of effort asthma coughs and colds analgesia headache and migraine drugs and mental disease epilepsy drugs and fertility haematinic drugs and the cellular elements of blood drugs in joint disease drugs and the skin Suggested further reading and study Index

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詳細情報

• NII書誌ID(NCID): BA27907300
• ISBN:
  • 0750621982
• 出版国コード: uk
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Oxford
• ページ数/冊数: xviii, 569 p
• 大きさ: 24cm
• 分類:
  • DC20 : 615.1
• 件名:
  • LCSH : Pharmacology