Molecular aspects of aging : report of the Dahlem Workshop on Molecular Aspects of Aging, Berlin, 1994, 13-18 February
著者
書誌事項
Molecular aspects of aging : report of the Dahlem Workshop on Molecular Aspects of Aging, Berlin, 1994, 13-18 February
(Life sciences research report, 56)
John Wiley & Sons, c1995
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注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
The subject of aging has emerged as a leading issue for biological and biomedical scientists. The elucidation of the underlying mechanisms of aging may constitute the most effective approach to the prevention or postponement of major geriatric disorders. An understanding of why individual subjects vary in their susceptibilities to these disorders will be of special significance to future medicine. This study examines the molecular aspects underlying genetic and physiological changes that occur with normal aging and geriatric disorders.
目次
- What Can Evolution Theory Tell Us About the Mechanisms of Aging?
- Nuclear Genes in Aging
- Aging and Genetic Instabilities
- Genes Controlling Programmed Cell Death: Relation to Mechanisms of Cell Senescence and Aging?
- Group Report: Research on Diverse Model Systems and the Genetic Basis of Aging and Longevity
- Free Radicals in Aging: Theories, Facts, and Artifacts
- Oxidative Damage to Mitochondrial DNA and its Relationship to Aging
- Is Oxidative Stress a Casual Factor in Aging?
- The Status of Oxidatively Modified Proteins as a Marker of Aging
- Group Report: Do Research Findings from Diverse Model Systems Support Oxidative Damage Theories of Aging?
- Mitochondrial DNA Mutations in Human Disease and Aging
- Does Aging Favour Translocation of Mitochondrial DNA Fragments to the Nuclear Genome?
- DNA Repair in Mitochondria: How is it Limited?
- Group Report: The Role of Bioenergetics and Mitochondrial DNA Mutations in Aging and Age-Related Diseases
- Pathogenic Mechanisms in Alzheimer Syndromes and Related Disorders
- The Role of Mitochondrial Dysfunction in Neurodegenerative Disease
- Lipoprotein Oxidation and Atherosclerosis
- Gerontology: The Study of Aging as the Study of Cancer
- Group Report: Do Common Underlying Mechanisms of Aging Contribute to the Pathogenesis of Major Geriatric Disorders?
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