Regulatory factors
著者
書誌事項
Regulatory factors
（Current topics in microbiology and immunology, 213/2 . Attempts to understand metastasis formation ; 2）
Springer, c1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Since the mid-1980s the molecular biology of tumour models has revealed the identification of several metastasis-related molecules. This work, in three parts, attempts to review approaches of their mechanisms, regulation and ways to treat their malignant alterations. In this second part the regulation of tumour progression and angiogenesis by cytokines, growth factors and motility factors is outlined.
目次
- List of Contents.- Regulation of Tumor Angiogenesis by Organ-Specific Cytokines.- Cytokine-Mediated Tumor-Endothelial Cell Interaction in Metastasis.- Angiogenesis-Regulating Cytokines: Activities and Interactions.- Adhesion Molecules and Tumor Cell-Vasculature Interactions: Modulation by Bioactive Lipid Molecules.- Brain Metastasis: Role of Trophic, Autocrine, and Paracrine Factors in Tumor Invasion and Colonization of the Central Nervous System.- Epithelial Differentiation and the Control of Metastasis in Carcinomas.- Regulation of Autocrine Motility Factor Receptor Expression in Tumor Cell Locomotion and Metastasis.- Metastasis-Related mts 1 Gene.- Alterations in Cell Cycle Control During Tumor Progression
- Effects on Apoptosis and the Response to Therapeutic Agents.- Differential Gene Expression in Tumor Metastasis: Nm23.- NM23/Nucleoside Diphosphate Kinase as a Transcriptional Activator of c-myc.- Role of Tiam 1 in Rac-Mediated Signal Transduction Pathways.- Influence of c-myc on the Progession of Human Breast Cancer.
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