Advances in the treatment of radiation injuries : proceedings of the 2nd Concensus Development Conference on the Treatment of Radiation Injuries, held in Bethesda, Maryland, USA on 14-17 April 1993
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Bibliographic Information
Advances in the treatment of radiation injuries : proceedings of the 2nd Concensus Development Conference on the Treatment of Radiation Injuries, held in Bethesda, Maryland, USA on 14-17 April 1993
(Advances in the biosciences, v. 94)
Pergamon, 1996
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes index
Description and Table of Contents
Description
The human health threat posed by exposure to ionizing radiation continues to present itself on many fronts. The most obvious, nuclear weapons proliferation, puts military personnel and civilians at risk not only during conflicts but also as a result of weapons production and storage. In addition, the peaceful applications of radioactive materials continue to expand in the fields of energy production, medical diagnosis and treatment, and scientific and medical research. This volume reflects the findings concerning the complex nature of radiation injuries and of potential prevention, assessment, and treatment strategies from the April 1993 Second Consensus Development Conference on the Treatment of Radiation Injuries. Leading researchers in 18 countries report their findings in 38 papers.
Table of Contents
Section headings and papers: Hematopoietic Syndrome or Bone Marrow Aplasia. G-CSF and GM-CSF in the management of acute marrow injury: focus on radiation-induced marrow aplasia (G.J. Lieschke). Cytokine therapy in bone marrow transplantation (M.R. Bishop, J.O. Armitage). Single and combination cytokine therapies for the treatment of radiation-induced hemopoietic injury (M.L. Patchen). Interleukin-3 and interleukin-3/GM-CSF combination therapy: results of clinical trials (A. Ganser et al. ). Studies to eliminate the absolute neutropenia high-dose chemotherapy (G. Spitzer et al. ). Thrombopoietic effects of recombinant human IL-6 in chemotherapy-induced myelosuppression (R.E. Isaacs). Hematopoietic growth factors in bone marrow failure states (D.F. Moore Jr., S. Vadhan-Raj). A nonhuman primate model for the study of effects of cytokines on hematopoietic reconstitution following chemotherapy-induced marrow damage (E.F. Winton et al. ). Ex vivo expansion of numbers of multipotential progenitor cells in human umbilical cord blood and considerations for the use of such cells for transplantation purposes (L. Ruggieri, H.E. Broxmeyer). Chemo and radiation protection with amifostine (R.L. Capizzi, P.S. Schein). In vivo application of interleukin-6 and granulocyte colony-stimulating factor for the treatment of acute radiation syndrome (Z. Pojda et al. ). Radiation-induced neutropenia reduces the extent of hepatic ischemia-reperfusion injury (R. Cachecho et al. ). Effect of cytokines on radiation-induced apoptosis in thymocytes and hematopoietic cells cultured in vitro (M.L. Hale et al. ). Sepsis. Selection of bacteria for animal models of sepsis (A.S. Cross et al. ). Therapeutic strategies in septic shock: tumor necrosis factor as a therapeutic target (J. Cohen et al. ). Interventions with anti-LPS, anti-TNF, and anti-coagulopathy measures in experimentally induced bacteremia/endotoxemia (S. Bahrami et al. ). Generation and preclinical development of CDP571, a human antibody engineered for TNF-alpha specificity (M.W. Bodmer). Strategies for modulation of systemic and tissue cykotine responses to sepsis (S.F. Lowry et al ). The roles of lipopolysaccharide-binding protein and bactericidal/permeability-increasing protein in regulating host responses to bacterial lipopolysaccharide (R.W. Scott, M.N. Marra). Soluble TNF receptors in lethal endotoxemia (K.M. Mohler et al. ). Survival enhancement and infection in mouse models of injury associated with radiation disasters (G.D. Ledney et al. ). L-carnitine in experimental septic shock (C. De Simone et al. ). Acute lung injury as a secondary response to endotoxin-induced mediators: prevention by HWA 138-a new xanthine derivative (S. Bahrami et al. ). Gastrointestinal Syndrome. Treatment strategies for radiation-induced gastrointestinal injuries (P.J. Gunter-Smith, A. Dubois). Elemental diets in treatment of gastrointestinal injury (A.H. McArdle).
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