Drugs of abuse, immunity, and infections

Bibliographic Information

Drugs of abuse, immunity, and infections

edited by Herman Friedman, Thomas W. Klein, and Steven Specter

CRC Press, c1996

Available at  / 2 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

During the past few decades, drugs of abuse, including marijuana, cocaine, opiates, and alcohol have been studied in detail by biomedical scientists in terms of their effects on the neurophysiology and psychological responses of individuals. Research over the last few years has provided increased knowledge about possible mechanisms by which such drugs increase the likelihood of infections in humans and experimental animals. In Drugs of Abuse, Immunity, and Infections prominent investigators review important new information concerning the effects of recreational drugs on susceptibility to infection by microorganisms. The volume examines the effects of drugs such as cocaine, morphine, marijuana, and opiates on immunity in humans and animals. It covers the molecular and cellular mechanisms of drug-induced immunosuppression and describes the overall enhanced susceptibility to infection in recreational drug users. It discusses the alteration of susceptibility to the retrovirus that causes the acquired immunodeficiency syndrome (AIDS) and the consensus that drugs of abuse may serve as a possible cofactor in the progression of AIDS. Drugs of Abuse, Immunity, and Infections also includes important information concerning public health aspects of drugs of abuse and infection.

Table of Contents

Drugs of Abuse and Immunity, G.G. Nahas Opiates, Infection, and Immunity, J.M. Risdahl, P. Peterson, and T. Mollitor Marijuana as an Immunomodulator, S. Specter Marijuana and Immune Modulation to Viruses, G. Cabral Morphine and Immunomodulation, T.K. Eisenstein Cocaine and Immune Response to Microorganisms, T. Klein Immunomodulation by Cocaine during Murine AIDS, R.R. Watson Morphine Addiction and Murine Toxoplasmosis, L.C. Chao Effects of Ethanol on Immunity to Infectious Agents Mediated by Th-1 and Th-2 T-Helper Lymphocytes, T.R. Jerrells Effect of Ethanol on Tumor Necrosis Factor and Cytokine Production in Lung Host Defenses, S. Nelson Mycobacterial Infection and Alcohol, B. Zwilling Bacterial Sepsis, Metabolism, and Alcohol, J.J. Spitzer Psychiatric Drugs and Infectious Diseases, M. Gibertini Autoimmunity and Drugs of Abuse, N. Rose

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