Adeno-associated virus (AAV) vectors in gene therapy
著者
書誌事項
Adeno-associated virus (AAV) vectors in gene therapy
（Current topics in microbiology and immunology, 218）
Springer-Verlag, c1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Viral vectors have been the favored delivery vehicle for gene therapy, and adeno-associated virus has become a candidate of great interest because of its biological properties which include site specific integration in human chromosome 19. In this volume methods of vector production and use in in vitro and in vivo experiments are described, including recent studies with hematopoietic stem cells and non-dividing cells. Various protocols for preparing recombinant AAV vectors and their intracellular delivery are extensively discussed. The first trial of AAV as vector for human gene therapy was conducted in late 1995.
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