Limb regeneration
著者
書誌事項
Limb regeneration
（Developmental and cell biology series）
Cambridge University Press, 1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The complex phenomenon of limb regeneration that occurs in some Amphibia involves unique molecular and cellular mechanisms. When a limb is amputated a new one is produced by the transformation of the remaining adult limb tissues into an embryonic-like cell mass, called the blastema. The blastema has the ability to subsequently redifferentiate into the various tissues that comprise a limb and therefore replace the lost part. It is argued that the same processes that are encountered in normal embryogenesis are reinitiated during regeneration. This is the first book that attempts to describe and analyse the mechanisms of both limb regeneration and patterning by incorporating the information obtained from older experiments with the many new advances in molecular and cellular biology that have occurred in recent years.
目次
- Preface
- Prologue
- 1. Capacity of limb regeneration in vertebrates
- 2. The amputation - the early events
- 3. The beginning of regeneration - wound epithelium
- 4. Dedifferentiation and origin of the blastema
- 5. Differentiation of the blastema
- 6. Nerve dependence of regeneration
- 7. Protein synthesis in the blastema
- 8. Limb cells in vitro
- 9. Tissue vs. Epimorphic regeneration
- 10. Bioelectricity and limb regeneration
- 11. Post-embryonic induction in amphibian limbs
- 12. Stimulation and inhibition of regeneration
- 13. Genetics and limb regeneration
- 14. Models for pattern formation
- 15. Morphogenetic properties of the blastema
- 16. The regeneration of positional information
- 17. Vitamin A and patterning
- 18. Hox genes and limb regeneration
- 19. Regenerating CSH developing limbs
- 20. Molecular advances
- References
- Index.
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