A textbook of drug design and development

Author(s)

Bibliographic Information

A textbook of drug design and development

edited by Povl Krogsgaard-Larsen, Tommy Liljefors, Ulf Madsen

Harwood Academic, c1996

2nd ed.

  • : pbk

Available at  / 4 libraries

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Note

Previous ed.: 1991

Includes bibliographical references and index

Description and Table of Contents

Description

This work starts with an overview of the topics of drug discovery and follows the individual stages of drug design and development, from the initial elucidation of a structure-activity relationship to the final processes of clincial evaluation and registration. Topics examined include the design of drugs for particular cellular aspects such as ion channels and receptors; specific classes of drug, such as peptidomimetics, antivirals and anticancer agents; the use of gene technology in pharmaceutical research; and the design and application of prodrugs to improve drug delivery.

Table of Contents

  • Drug discovery - an overview
  • structural and phsyicochemical factors in drug action
  • computer-aided development of three-dimensional pharmacophore models
  • gene technology in pharmaceutical research and production
  • receptors
  • radiotracers - synthesis and use in imaging
  • ion channels
  • excitatory amino acid receptors
  • enzymes and enzyme inhibitors
  • bioinorganic chemistry
  • design and application of prodrugs
  • peptides and peptidomimetics
  • classical antiviral agents and design of new antiviral agents
  • anticancer agents
  • drug development - from discovery to marketing.

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Details

  • NCID
    BA28382869
  • ISBN
    • 3718658666
    • 3718658674
  • Country Code
    ne
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Amsterdam
  • Pages/Volumes
    543 p., [10] p. of plates
  • Size
    25 cm
  • Classification
  • Subject Headings
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