Biomedical frontiers of fluorine chemistry : developed from symposia sponsored by the Division of Fluorine Chemistry and the Division of Medicinal Chemistry

Bibliographic Information

Biomedical frontiers of fluorine chemistry : developed from symposia sponsored by the Division of Fluorine Chemistry and the Division of Medicinal Chemistry

Iwao Ojima, James R. McCarthy, John T. Welch, editor

(ACS symposium series, 639)

American Chemical Society, c1996

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Includes bibliographical references and index

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Description

Reviews recent research on fluorine-containing, biologically relevant molecules in biology and medicinal chemistry. The text reports applications of bioactive organofluorine compounds as enzyme inhibitors, antithrombotics, anticancer agents, antiviral agents, antibacterials, central nervous system agents and antifungals and antimalarial agents. It also discusses the use of fluorine-containing amino acids as probes for investigating biomedical problems, including applications in fluorine-19 NMR, neurotransmission investigations, and fluorine-18 labelled tracers for positron emission tomography.

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