Insect cell cultures : fundamental and applied aspects

著者

    • Vlak, J. M.

書誌事項

Insect cell cultures : fundamental and applied aspects

edited by J.M. Vlak... [et al.]

(Current applications in cell culture engineering, v. 2)

Kluwer, 1996

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内容説明・目次

内容説明

Insect Cell Cultures: Fundamental and Applied Aspects is a comprehensive reference work, covering the key issues involved in nearly 30 review papers: cell lines (development, characterisation, physiology, cultivation and medium design); viruses (virus-cell interactions, replication, recombinant construction, infection kinetics, post-translational modification and passage effects); engineering (shear, bioreactors including perfusion, immobilisation, scale-up and modelling, downstream processing); applications; economics and regulatory aspects. For cell biologists, biochemists, molecular biologists, virologists, immunologists and other basic and applied disciplines related to cell culture engineering, both academic and industrial.

目次

  • Preface. Development and characterization of insect cell lines
  • D. Lynn. New approaches to insect tissue culture
  • D. Baines. Transgenic insect cells: mosquito cell mutants and the dihydrofolate reductase gene
  • A.M. Fallon. Insect cell physiology
  • R. Bhatia. Insect cell cultivation: growth and kinetics
  • G. Schmid. Medium design for insect cell culture
  • E.-J. Schlaeger. Baculovirus-insect interactions
  • G.W. Blissard. Replication patterns and cytopathology of cells infected with baculoviruses
  • G.V. Williams, P. Faulkner. Construction of baculovirus recombinants
  • P.A. Kitts. Passage effect of virus infection in insect cells
  • P.J. Krell. Post-translational modifications in insect cells
  • H.-D. Klenk. Productivity of insect cells for recombinant proteins
  • J.E. Maruniak. Chaperone and foldase coexpression in the baculovirus-insect cell expression system
  • M.J. Betenbaugh, et al. Shear sensitivity of insect cells
  • J.J. Chalmers. Insect cell bioreactors
  • S.N. Agathos. Perfusion for the production of recombinant proteins in insect cells
  • V. Jager. Immobilization of insect cells
  • Jian-Yong Wu, M.F.A. Goosen. Modelling baculovirus infection of insect cells in culture
  • J.F. Power, L.K. Nielsen. Scale up aspects of sparged insect-cell bioreactors
  • J. Tramper, et al. Oxygen gradients in small and big sparged insect-cell bioreactors
  • J. Tramper, et al. Downstream processing of insect cell cultures
  • A.R. Bernard, et al. Parvovirus diagnostics and vaccine production in insect cells
  • J.I. Casal. Classical swine fever virus diagnostic and vaccine production in insect cells
  • M.M. Hulst, R.J.M. Moormann. Production of multidomain complement glycoproteins in insect cells
  • P. Zavodski, S. Cseh. Economicsof baculovirus insect cell production systems
  • D.J. Rhodes. Safety aspects of insect cell culture
  • G. Stacey. Regulatory issues in the use of insect-cell culture
  • F.L.J. van Lier. Keyword index.

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