High-pressure effects in molecular biophysics and enzymology
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書誌事項
High-pressure effects in molecular biophysics and enzymology
Oxford University Press, 1996
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Written by the best researchers in the field, this timely book explores the use of high pressure in connection with spectroscopy as a research tool in biophysics and biochemistry. It covers subjects such as pressure tunning spectroscopy for investigating molecular interactions; high-pressure FT-IR studies of the secondary structure of proteins; structural, functional, and kinetic aspects of nucleic acid-protein complexes with pressure; sequence, salt, charge, and the
stability of DNA at high pressure; steady-state enzyme kinetics at high pressure; membrane-free volume with bulky lipid concentration by regular distribution; and pressure and temperature induced inactivation of microorganisms.
目次
- 1. Resolution of the Ambiguity of Vam't Hoff Plots by the Effect of Pressure Upon the Equilibrium
- 2. Pressure Tunning Spectroscopy - A Tool for Investigating Molecular Interactions
- 3. Use of Partial Molar Volumes of Model Compounds in the Interpretation of High-Pressure Effects on Proteins
- 4. Pressure-tunning Spectroscopy of Proteins: Fourier Transform Infrared Studies in the Diamond Anvil Cell
- 5. Temperature and Pressure-Induced Unfolding of a Mutant of Staphylococcal Nuclease A
- 6. Pressure-Jump Relaxation Kinetics of Unfolding and Refolding Transitions of Staphylococcal Nuclease and Proline Isomerization Mutants
- 7. High-Pressure FT-IR Studies of the Secondary Structure of Proteins
- 8. High-Pressure NMR Studies of the Dissociation of Arc Repressor and the Cold Denaturation of Ribonuclease A
- 9. Exploring Structural, Functional, and Kinetic Aspects of Nucleic Acid-Protein Complexes with Pressure: Nucleosomes and RNA Polymerase
- 10. Pressure and Cold Denaturation of Proteins, Protein-DNA Complexes, and Viruses
- 11. Sequence, Salt, Charge, and the Stability of DNA at High Pressure
- 12. The Application of Pressure Relaxation to the Study of Substrate Binding to Cytochrome P versus Temperature, Pressure, and Viscosity
- 13. Pressure Effects on the Ligand Binding Kinetics for Hemoproteins and Their Site-Directed Mutants
- 14. Steady-State Enzyme Kinetics at High Pressure
- 15. Transient Enzyme Kinetics at High Pressure
- 16. The Effects of High Pressure on the Allosteric Properties of Phosphofructokinase from Escherichia coli
- 17. Correlation Field Splitting of Chain Vibrations: Structure and Dynamics in Lipid Bilayers and Biomembranes
- 18. High Pressure Effects on the Structure and Phase Behavior of Model Membranes Systems
- 19. Membrane-Free Volume with Bulky Lipid Concentration by Regular Distribution: A Functionally Important Membrane Property Explored by Pressure Studies of Pyrene-Labelled Phosphatidylcholine
- 20. NMR Studies of the Order and Dynamics of Dipalmitoylphosphatidylcholine Bilayers as a Function of Pressure
- 21. The Effects of Increased Viscosity on the Function of Integral Membrane Proteins
- 22. Pressure and Temperature Induced Inactivation of Microorganisms
- 23. Osmotic and Hydrostatic Pressure as Tools to Study Molecular Recognition
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