Ion channels : molecules in action
Author(s)
Bibliographic Information
Ion channels : molecules in action
Cambridge University Press, 1996
- : hbk
- : pbk
Available at / 33 libraries
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National Institutes of Natural Sciences Okazaki Library and Information Center図
: hbk464.1/Io9307823821
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Ion channels are crucial components of living cells. Situated in the cell's membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly.
Table of Contents
- Preface
- 1. Introduction
- 2. Ions on the move
- 3. Investigating channel activity
- 4. Molecular structures
- 5. Permeability and selectivity
- 6. Gating and modulation
- 7. Drugs and toxins
- 8. Dysfunctional channels in human disease
- 9. Not the last word
- References
- Index.
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