Glial cell development : basic principles and clinical relevance
著者
書誌事項
Glial cell development : basic principles and clinical relevance
(The molecular and cellular neurobiology series)
BIOS Scientific, 1996
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注記
Includes bibliographies and index
内容説明・目次
内容説明
Glial cell function and development have now become a major focus of research in the neurosciences. Distinct glial progenitors have been identified, key glial genes have been cloned and the growth factor regulation of glial survival, proliferation and function is being unravelled. as a result, it will soon be possible to understand, at the molecular level, some vital glial functions, such as myelination and regulation of axon growth and repair. From the viewpoint of neuropathology, these studies provide exciting clues about how glial cells might be involved in nervous system disorders. This should result in the development of therapeutic strategies involving the transplantation of normal or genetically modified glial cells into damaged nervous tissue. In this book, leading researchers review recent advances in the knowledge of all classes of glia, and describes how this knowledge is now being harnessed for the treatment of human disease.
目次
1: H J S Stewart, R Mirsky & K R Jessen: The Schwann cell lineage: embryonic and early postnatal development. 2: J E Goldman: Developmental origins of astrocytes. 3: W D Richardson, N P Pringle, W -P Yu, E J Collarini & A Hall: Origins and early development of oligodendrocytes. 4: B A Barres & M C Raff: Axonal control of oligodendrocyte development. 5: D R Colman, J P Doyle, D D'Urso, K Kitagawa, L Pedraza, M Yoshida & A M Fannon: Speculations on myelin sheath evolution. 6: L D Hudson, N Ko & J G Kim: Control of myelin gene expression. 7: V H Perry: Microglia in the developing and mature central nervous system. 8: K-A Nave: Myelin-specific genes and their mutations in the mouse. 9: S S Scherer and J L Salzer: Axon-Schwann cell interactions during peripheral nerve degeneration and regeneration. 10: H Vickland & J Silver: The role of astrocytes in axon guidance during development and repair. 11: W F Blakemore, R J M Franklin & M Noble: Glial cell transplantation and the repair of demyelinating lesions. 12: G Raisman: Transplantation of Schwann cells into the CNS: potential for repair of tract lesions. 13: A J Auld: The role of glia in the development of the insect nervous system
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