Novel chemotherapeutic agents : preactivation in the treatment of cancer and AIDS
著者
書誌事項
Novel chemotherapeutic agents : preactivation in the treatment of cancer and AIDS
（Medical intelligence unit）
Springer , R.G. Landes, c1996
- :International
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book is about a discovery termed "preactivation" that is considered a major breakthrough in photodynamic therapy and in drug development. The process of preactivation generates previously unknown chemotherapeutic agents that are not only effective against malignancies and viral infections, but are also easily tolerated.
目次
1. Challenges and Opportunities in New Drug Development.- 2. Preactivation-Discovery and Biological Effects of Novel Chemotherapeutic Agents.- 3. Photochemistry and Photophysics of Merocyanine 540.- 4. Preclinical Studies of Preactivated Merocyanine 540 and Merodantoin.- 5. The Role of Topoisomerases and Apoptosis in the Mechanism of Action of Preactivated Compounds.- 6. Modulation of Oncogenes with Preactivated Compounds.- Epilogue.
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