Pharmaceutical statistics : practical and clinical applications

書誌事項

Pharmaceutical statistics : practical and clinical applications

Sanford Bolton

(Drugs and the pharmaceutical sciences, v. 80)

Dekker, c1997

3rd ed

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注記

Includes bibliographical references

内容説明・目次

内容説明

This edition offers new and expanded information on recent developments in stability data analysis, concepts of statistical outliners, bioequivalence studies, problems in sampling and devising limits for product release, covariance analysis and tolerance intervals, multiple endpoints and clinical data analysis, and more. College and university bookstores may order five or more copies at a special student price which is available upon request from Marcel Dekker.

目次

  • Basic definitions and concepts
  • data graphics
  • introduction to probability - the binomial and normal probability distributions
  • choosing samples
  • statistical inference - estimation and hypothesis testing
  • sample size and power
  • linear regresison and correlation
  • analysis of variance
  • factoral designs
  • transformations and outliers
  • experimental design in clinical trials
  • quality control
  • validation
  • consumer testing
  • nonparametric methods
  • optimization techniques. Appendices: some properties of the variance
  • comparison of slopes and testing of linearity - determination of relative potency
  • multiple regression
  • tables
  • outlier tests and chemical assays
  • should a single unexplained failing assay be reason to reject a batch?
  • answers to exercises.

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