書誌事項

The molecular basis of cellular defence mechanisms

[editors, Gregory R. Bock (organizer) and Jamie A. Goode]

(Ciba Foundation symposium, 204)

John Wiley, 1997

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注記

Symposium on the molecular basis of cellular defence mechanisms, held at the Walter and Eliza Hall Institute of Medical Research, Melbourne 1996

Includes bibliographical references and indexes

内容説明・目次

内容説明

The body's defence against invading microorganisms is delegated to two sets of haemopoietic cells. These share their ancestral origin from multipotential haemopoietic stem cells and they need to be produced continuously throughout life. This biology requires complex programmes of controlled cell division, differentiation commitment and maturation.

目次

  • How Do Stem Cells Decide What to Do?
  • The Structural Basis of GM-CSF Receptor Action
  • The Molecular Control of Granulocytes and Macrophages
  • CSF-Deficient Mice: What Have They Taught Us?
  • Clinical Benefits of Improving Host Defences with G-CSF
  • T-Cell Receptor Biochemistry, Repertoire Selection and Structure
  • Immunology Learnt From Viruses
  • Dendritic Cells and T-Lymphocytes: Development and Functional Interactions
  • Immunoregulation by Cytokines of T-Cell Subsets
  • T-Cell Tolerance and Autoimmunity
  • Control of the Sizes and Contents of Precursor B Repertoires in Bone Marrow
  • Checkpoints and Thresholds for Censoring Self-Reactive B-Lymphocytes.

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