Graft-vs.-host disease
著者
書誌事項
Graft-vs.-host disease
Marcel Dekker, c1997
2nd ed., rev. and expanded
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注記
Includes index
内容説明・目次
内容説明
With detailed contributions from more than 40 leading authorities on the topic, this Third Edition comprehensively explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GVHD)-offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GVHD prevention and treatment.
目次
The Pathophysiology of Graft-vs.-Host Disease. Animal Models of Graft-vs.-Host Disease. Graft-vs.-Host Disease as a Th1-Type Process: Regulation by Th2-Type Cells. Role of T-Cell Costimulation and Regulatory Cells in Allogeneic Hematopoietic Cell Transplantation. Chemokines and Graft-vs.-Host Disease. Graft-vs.-Leukemia Effects. The Immune System in Graft-vs.-Host Disease: Target and Effector Organ. Pathology and Pathogenesis of Cutaneous Graft-vs.-Host Disease. Graft-vs.-Host Disease of the Liver. Intestinal Graft-vs.-Host Disease. The Pathophysiology of Lung Injury After Hematopoietic Stem Cell Transplantation. Clinical Spectrum of Acute Graft-vs.-Host Disease. Role of Minor Histocompatibility Antigens in the Development of Graft-vs.-Host Disease and Graft-vs.-Leukemia Reactivity. Advances in Tissue Typing and Their Potential Impact on GVHD Incidence and Severity. Immunosuppression and Immunophilin Ligands: Cyclosporin, Tacrolimus, and Sirolimus. Prophylaxis and Treatments of Acute Graft-vs.-Host Disease. Graft Manipulation to Prevent Graft-vs.-Host Disease. Graft-vs.-Host Disease in Nonmyeloablative Transplant. Adoptive Immunotherapy in Stem Cell Transplantation. Clinical Spectrum and Therapeutic Approaches to Chronic Graft-vs.-Host Disease. Recent Advances and Future Directions.
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