Principles of antineoplastic drug development and pharmacology

著者

書誌事項

Principles of antineoplastic drug development and pharmacology

edited by Richard L. Schilsky, Gérard A. Milano, Mark J. Ratain

（Basic and clinical oncology, 9）

M. Dekker, c1996

大学図書館所蔵 件 / 全4件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Reviews the principles of drug development and clinical pharmacology applicable to all classes of anticancer drugs. Covers every aspect of drug development--from drug discovery to approval and routine use. Details how the successful application of pharmacological principles can improve drug delivery, individualized dosing, and the circumvention of drug resistance; elucideates proven strategies for widening the therapeutic margin between antitumor effects and severe toxicity; and more.

目次

Principles of Drug Development Cancer Drug Screening, Michael R. Grever The Human Tumor-Cloning Assay, Axel-R. Hanauske, Susan G. Hilsenbeck, and Daniel D. Von Hoff Phase I Clinical Trial Design, Rosemarie Mick The New Drug Approval Process: Clinical and Regulatory Aspects, Renzo Canetta Development of Biological Agents, Rosemary Mazanet, Mary Ann Foote, and George Morstyn Principles of Antineoplastic Pharmacology Clinical Pharmacology of Anticancer Drugs, B. W. Berry and Charles Erlichman Principles of Pharmokinetics and Pharmacodynamics, Mark J. Ratain and Rosemary Mick Biochemical Modulation of Cancer Chemotherapy, George A. Sotos and Carmen J. Allegra Drug Interactions in Cancer Chemotherapy, Francois Lokiec Drug-Radiation Interactions, Everett E. Vokes Principles of Chemotherapy Interaction with Biological Agents, Mario Sznol, Christine L. Carter and Dan L. Longo Hematopoietic Growth Factors and Cancer Chemotherapy, Michael S. Gordon Dose Intensity, William M. Hryniuk Principles of Chemotherapy Dosing Polymorphic Drug-Metabolizing Enzymes, Zhihong Lu and Robert B. Diasio Human Cytochrome P-450, Frank J. Gonzalez Cellular Pharmacodynamics of Anticancer Drugs, Peter J. O'Dwyer, Thomas C. Hamilton, Kang-Shen Yao, Robert F. Ozols, and James M. Gallo Cancer Chemotherapy in the Elderly, Maurice Schneider Cancer Chemotherapy and Pharmacology in Children, Steven Weitman and Barton A. Kamen Adaptive Control of Drug Dosage Regimens: Basic Concepts, Relevant Issues, and Clinical Applications, Roger W. Jelliffe Individualized Dosing of Anticancer Drugs, Alan V. Boddy and A. Hilary Calvert Principles of Drug Resistance Multidrug Resistance, Ahmad R. Safa DNA Topoisomerases and Tumor Cell Resistance to Their Inhibitors, William T. Beck The Glutathione System and Drug Resistance, Gerald Batist, Robyn L. Schecter, and Moulay A. Alaoui-Jamali Importance of DNA Repair in Cancer Chemotherapy, M. Eileen Dolan Resistance to Antimetabolites, Godefridus J. Peters and Gerrit Jansen Principles of Drug Delivery Targeted Drug Delivery, Pramod K. Gupta, John B. Cannon, and Anil Kumar Tibrewal Intra-Arterial Chemotherapy, William D. Ensminger Intraperitoneal Chemotherapy, Maurie Markman Intrathecal Chemotherapy, Susan M. Blaney and David G. Poplack Systemic Infusional Chemotherapy, Jacob J. Lokich and Norwood Anderson Circadian Pharmacodynamics, William J. M. Hrushesky, Robert de W. Marsh, and Patricia A. Wood

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