The endothelium in clinical practice : source and target of novel therapies

Bibliographic Information

The endothelium in clinical practice : source and target of novel therapies

edited by Gabor M. Rubanyi, Victor J. Dzau

(Fundamental and clinical cardiology, v. 29)

M. Dekker, c1997

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Includes bibliographical references and index

Description and Table of Contents

Description

Highlighting the transition from basic research to clinical applications, this unique reference presents the endothelium as both the source and the target of novel therapeutic concepts and discusses the involvement of the endothelium in mainstream approaches to the treatment of various conditions.

Table of Contents

The Endothelium as the Source of Novel Therapies Prostacyclin (Prostaglandin I2) and Atherosclerosis, Karsten Schroer Prostacyclin and Thromboxane: Role in Ischemic Heart Disease, Jawahar L. Mehta and Baichun C. Yang Clinical Use of Prostacyclins, John A. Dormandy and Glyn Belcher Nitric Oxide Synthases: Enzymology and Mechanism-Based Inhibitors, John F. Parkinson and Gary Phillips Endothelin: From Basic to Pathophysiological Research, Katsutoshi Goto Transmigration of Leukocytes, B. Stein, Y. Khew-Goodall, J. Gamble, and M. A. Vadas Transforming Growth Factor-b and Cardiovascular Protection, David J. Grainger and James C. Metcalfe Coagulation Factors, Michael Kalafatis, Jack O. Egan, and Kenneth G. Mann The Endothelium as a Target for Novel Therapies Endothelial Dysfunction and Vascular Disease, Paul M. Vanhoutte, Louis Perrault, and Jean Paul Vilaine Complement and Endothelium: Novel Complement-Inhibitory Therapeutics, Una S. Ryan The Receptor for Advanced Gycation Endproducts: Implications for the, Development of Diabetic Vascular Disease, Osamu Hori, Shi Du Yan, and Ann Marie Schmidt Hypertension, Pierre Moreau and Thomas F. Luscher Arterial Restenosis, Michael A. Reidy and Stephen M. Schwartz Pathobiology and Clinical Consequences of Plaque Rupture, Richard Gallo, Juan J. Badimon, James H. Chesebro, Valentin Fuster, and Lina Badimon Isoprostanes and Antioxidant Therapy in Human Diseases, Emma A. Meagher and Garrett A. FitzGerald Vasculoprotection by Estrogen Contributes to Gender Difference in Cardiovascular Diseases: Potential Mechanism and Role of Endothelium, Katalin Kauser and Gabor M. Rubanyi Lipoprotein(a): Insights from Transgenic Mice, Steven D. Hughes and Edward M. Rubin Gene Therapy Gene Therapy with Vascular Endothelial Growth Factor, Jeffrey M. Isner Vascular Disease and the Prospect of Gene Therapy, Heiko E. von der Leyen and Victor J. Dzau

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