Fetal and neonatal brain injury : mechanisms, management, and the risks of practice
著者
書誌事項
Fetal and neonatal brain injury : mechanisms, management, and the risks of practice
(Oxford medical publications)
Oxford University Press, 1997
2nd ed
- タイトル別名
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Fetal & neonatal brain injury : mechanisms, management and therisk of practice
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book evaluates the numerous events in pregnancy, labour, and post-partum care that can lead to brain damage in newborn infants. The mechanisms by which the brain is damaged, as well as the approaches to treatment and most importantly, prevention of injury are delineated. This book is intended for fetal medicine physicians, neonatalogists, paediatricians, paediatric neurologists, neuro-radiologists, neuro-pathologists, obstetricians.
目次
Section I: Possible causes of acquired fetal and neonatal brain injury. 1: Epidemiology of perinatal asphyxia. 2: Mechanisms of Ischaemic-cell injury. 3: Ischaemia-Reperfusion Injury. 4: Experimental models of perinatal brain inury. 5: Endogenous neuroprotective mechanisms: Their implications for therapeutic intervention. 6: Fetal response to asphyxia. 7: Prematurity and complications of labor and delivery. 8: Intrauterine growth retardation. 9: Congenital malformations of the brain. 10: Haemorrhagic lesions of the central nervous system. Section II: Environmental causes of acquired fetal and neonatal brain injury. 1: The use of intrapartum fetal heart rate monitoring to reduce perinatal asphyxia in the term infant. 2: Tocolytic therapy for preterm labor. 3: Fetal and neonatal injury as a consequence of maternal substance abuse. 4: Neurological sequelae of congenital infections. 5: Neonatal bacterial meningitis. 6: Perinatal HIV infection. 7: Metabolic disorders of the mother affecting the fetus. Setion III: Diagnosing the infant with asphyxia. 1: Hypoxemic-ischaemic encephalopathy. 2: Use of the electroencephalogram in assessing acute brain damage in the newborn. 3: Imaging of neonatal hypoxic-ischaemic cerebral damage. 4.: Correlation of clinical findings and timing of the asphyxial event. 5.: Neonatal asphyxic brain injury. Section IV: Management of the depressed or neurologically dysfunctional infant. 1: Immediate management. 2: Extended management. 3: The management of neonatal seizures. 4: Nutritional support of the asphyxiated infant. Section V: Specific abnormalities associated with fetal and neonatal brain injury. 1: Hypoglycemia in the neonate. 2: Hemaologic disorders: anemia, polycythemia and hyperbilirubinemia. 3: Acidosis/alkalosis. 4: Hydrops fetalis. 5: Polycythemia. 6: Meconium staining and the meconium aspiration syndrome. 7: Persistent pulmonary hypertension of the newborn
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