Textbook of receptor pharmacology

著者

書誌事項

Textbook of receptor pharmacology

edited by John C. Foreman and Torben Johansen

CRC Press, c1996

大学図書館所蔵 件 / 全11件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Students and researchers alike can benefit from University College London's long history of major contributions to receptor pharmacology with the Textbook of Receptor Pharmacology. This book evolved from the college's advanced receptor pharmacology course, developed by a pharmacology department that has been led by such renowned scientists as Clark, Gaddum, Schild, and Black. The text's innovative format unites four major approaches to the study of receptors: molecular biology; quantitative functional studies of agonists and antagonists; ligand binding; and signal transduction systems - a combination unprecedented in this type of book. The Textbook of Receptor Pharmacology includes practice problems to facilitate comprehension and retention of material. It also contains helpful appendices explaining the simple mathematics used in the text. Take advantage of this comprehensive, time-saving resource on receptor pharmacology, a rapidly-expanding research area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.

目次

DRUG-RECEPTOR INTERACTION Classical Approaches to the Study of Drug-Receptor Interactions, D.H. Jenkinson MOLECULAR STRUCTURE OF RECEPTORS Molecular Structure of G-Protein Coupled Receptors, T.W. Schwartz Molecular Structure of Ligand-Gated Ion Channels, J. Egebjerg Molecular Structure of Tyrosine Kinase-Linked Receptors, S. Gammeltoft and C.R. Kahn LIGAND BINDING STUDIES OF RECEPTORS Direct Measurement of Drug Binding to Receptors, D.G. Haylett SIGNAL TRANSDUCTION SYSTEMS Introduction to Signal Transduction, J.C. Foreman Receptors Linked to Ion Channels: Activation and Block, A.J. Gibb G-Proteins, A.C. Dolphin Phospholipases and Phosphokinases: A Source of Lipid-Derived Second Messengers, S. Cockcroft Intracellular Calcium, O.H. Peterson, C.C.H. Petersen, and H. Kasai Protein Kinase C and Diacylglycerol, R. Sagi-Eisenberg Cyclic Nucleotides, J.C. Foreman Signal Transduction Through Protein Tyrosine Kinases, I. Kramer RECEPTORS AS PHARMACEUTICAL TARGETS Receptors as Pharmaceutical Targets, J.W. Black INDEX Some chapters include problems (and solutions) and lists for further reading.

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