Chromosomal translocations and oncogenic transcription factors
著者
書誌事項
Chromosomal translocations and oncogenic transcription factors
(Current topics in microbiology and immunology, 220)
Springer-Verlag, c1997
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The articles in this volume document the many varied genetic and biochemical alterations sustained by human proto-oncogenic transcription factors which result in diverse neoplastic processes. It offers insights into how normal programmes of gene expresion can be subverted by the action of single transcription factors resulting in a specific tumour type. The text prompts the idea of exploiting these tumour-specific alterations as diagnostic, prognostic tools, or as selective therapeutic targets.
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