Chromosomal translocations and oncogenic transcription factors
Author(s)
Bibliographic Information
Chromosomal translocations and oncogenic transcription factors
（Current topics in microbiology and immunology, 220）
Springer-Verlag, c1997
Available at 14 libraries
Note
Includes bibliographical references and index
Description and Table of Contents
Description
The articles in this volume document the many varied genetic and biochemical alterations sustained by human proto-oncogenic transcription factors which result in diverse neoplastic processes. It offers insights into how normal programmes of gene expresion can be subverted by the action of single transcription factors resulting in a specific tumour type. The text prompts the idea of exploiting these tumour-specific alterations as diagnostic, prognostic tools, or as selective therapeutic targets.
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