Heat shock proteins and cytoprotection : ATP-deprived mammalian cells

Bibliographic Information

Heat shock proteins and cytoprotection : ATP-deprived mammalian cells

Alexander E. Kabakov, Vladimir L. Gabai

(Molecular biology intelligence unit)

R.G.Landes, 1997

  • International

Available at  / 10 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

This text considers a recently discovered function of heat shock proteins (HSP): the adaptation of mammalian cells to energy deficiency. It discusses the following problems: how do cells sense transient ATP decrease and why does it evoke heat shock response? How can HSPs protect cells from damage and death and what are their intracellular targets? What may be a clinical application of HSP-mediated adaptation to ischaemia?

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